HsaEX0022576 @ hg19
Exon Skipping
Gene
ENSG00000100393 | EP300
Description
E1A binding protein p300 [Source:HGNC Symbol;Acc:3373]
Coordinates
chr22:41537052-41543950:+
Coord C1 exon
chr22:41537052-41537226
Coord A exon
chr22:41542743-41542820
Coord C2 exon
chr22:41543841-41543950
Length
78 bp
Sequences
Splice sites
3' ss Seq
ATTTCTCTTTTTTACTCTAGATG
3' ss Score
10.1
5' ss Seq
CTGGTAAAT
5' ss Score
6.06
Exon sequences
Seq C1 exon
GCGGAATACTACCACCTTCTAGCTGAGAAAATCTATAAGATCCAGAAAGAACTAGAAGAAAAACGAAGGACCAGACTACAGAAGCAGAACATGCTACCAAATGCTGCAGGCATGGTTCCAGTTTCCATGAATCCAGGGCCTAACATGGGACAGCCGCAACCAGGAATGACTTCTA
Seq A exon
ATGGCCCTCTACCTGACCCAAGTATGATCCGTGGCAGTGTGCCAAACCAGATGATGCCTCGAATAACTCCACAATCTG
Seq C2 exon
GTTTGAATCAATTTGGCCAGATGAGCATGGCCCAGCCCCCTATTGTACCCCGGCAAACCCCTCCTCTTCAGCACCATGGACAGTTGGCTCAACCTGGAGCTCTCAACCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100393_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.734 A=0.915 C2=1.000
Domain overlap (PFAM):
C1:
PF0217211=KIX=PD(23.5=32.2),PF068866=TPX2=PD(81.6=52.5)
A:
PF139001=GVQW=PD(10.0=66.7)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGGCATGGTTCCAGTTTCCA
R:
CTCCAGGTTGAGCCAACTGTC
Band lengths:
168-246
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)