HsaEX0025105 @ hg19
Exon Skipping
Gene
ENSG00000142449 | FBN3
Description
fibrillin 3 [Source:HGNC Symbol;Acc:18794]
Coordinates
chr19:8151084-8152831:-
Coord C1 exon
chr19:8152709-8152831
Coord A exon
chr19:8151961-8152095
Coord C2 exon
chr19:8151084-8151209
Length
135 bp
Sequences
Splice sites
3' ss Seq
CTGTCTCTGGTCATCCGAAGATG
3' ss Score
6.94
5' ss Seq
CAGGTATGG
5' ss Score
9.99
Exon sequences
Seq C1 exon
ACATCGACGAATGCTCCCTGAACCCGCTGCTCTGTGCCTTCCGCTGCCACAATACCGAGGGCTCCTACCTGTGCACCTGTCCAGCCGGCTACACCCTGCGGGAGGATGGGGCCATGTGTCGAG
Seq A exon
ATGTGGACGAGTGTGCAGATGGTCAGCAGGACTGCCACGCCCGGGGCATGGAGTGCAAGAACCTCATCGGTACCTTCGCGTGCGTCTGTCCCCCAGGCATGCGGCCCCTGCCTGGCTCTGGGGAGGGCTGCACAG
Seq C2 exon
ATGACAATGAATGCCACGCTCAGCCTGACCTCTGTGTCAACGGCCGCTGTGTCAACACCGCGGGCAGCTTCCGGTGCGACTGTGATGAGGGATTCCAGCCCAGCCCCACCCTTACCGAGTGCCACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000142449_MULTIEX1-43/43=42-C2
Average complexity
S
Mappability confidence:
98%=98=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=95.2),PF0764510=EGF_CA=PU(0.1=0.0)
A:
PF0764510=EGF_CA=WD(100=95.7),PF0764510=EGF_CA=PU(0.1=0.0)
C2:
PF0764510=EGF_CA=WD(100=95.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCGACGAATGCTCCCTGAAC
R:
CGTGGCACTCGGTAAGGGT
Band lengths:
247-382
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)