HsaEX0028544 @ hg19
Exon Skipping
Gene
ENSG00000161835 | GRASP
Description
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein [Source:HGNC Symbol;Acc:18707]
Coordinates
chr12:52400724-52404719:+
Coord C1 exon
chr12:52400724-52401049
Coord A exon
chr12:52402974-52403023
Coord C2 exon
chr12:52404665-52404719
Length
50 bp
Sequences
Splice sites
3' ss Seq
CTGACCATCTTACTGCCCAGGGC
3' ss Score
7.09
5' ss Seq
GCGGTGAGT
5' ss Score
10.49
Exon sequences
Seq C1 exon
CCGGCTGGCATCCCCCAGCCGCCGCCAGCCCCGCCGAGGGGAGCCAGCGCCGTCTCTGAGGGGCGTCCGGCGCCGGAGCCATGACCCTCCGCCGACTCAGGAAGCTGCAGCAGAAGGAGGAGGCGGCGGCCACCCCGGACCCCGCCGCCCGGACTCCCGACTCGGAAGTCGCGCCCGCCGCTCCGGTCCCGACCCCGGGACCCCCTGCCGCAGCCGCCACCCCTGGGCCCCCAGCGGACGAGCTGTACGCGGCGCTGGAGGACTATCACCCTGCCGAGCTGTACCGCGCGCTCGCCGTGTCCGGGGGCACCCTGCCCCGCCGAAAG
Seq A exon
GGCTCAGGATTCCGCTGGAAGAATCTCAGCCAGAGTCCTGAACAGCAGCG
Seq C2 exon
GAAAGTGCTGACGTTGGAGAAGGAGGATAACCAGACCTTCGGCTTTGAGATCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000161835_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.707 A=0.824 C2=0.526
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0059519=PDZ=PU(18.4=84.2)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCGCTGGAGGACTATCACCC
R:
CGAAGGTCTGGTTATCCTCCT
Band lengths:
116-166
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)