HsaEX0031555 @ hg19
Exon Skipping
Gene
ENSG00000129351 | ILF3
Description
interleukin enhancer binding factor 3, 90kDa [Source:HGNC Symbol;Acc:6038]
Coordinates
chr19:10794593-10798384:+
Coord C1 exon
chr19:10794593-10794646
Coord A exon
chr19:10795092-10795152
Coord C2 exon
chr19:10798022-10798384
Length
61 bp
Sequences
Splice sites
3' ss Seq
TCTGTCTCCCCCTTTTGTAGGTG
3' ss Score
11.91
5' ss Seq
AAAGTATTG
5' ss Score
-1.65
Exon sequences
Seq C1 exon
GTGCTGGGTATGGAAGCTATGGGTACGGAGGCAACTCGGCGACAGCAGGCTACA
Seq A exon
GTGACTTTTTCACAGACTGCTACGGCTATCATGATTTTGGGTCTTCCTAGAGCGTCTAAAA
Seq C2 exon
GTCAGTTCTACAGCAACGGAGGGCATTCTGGGAATGCCAGTGGCGGTGGCGGCGGGGGCGGTGGTGGCTCCTCCGGCTATGGCTCCTACTACCAAGGTGACAACTACAACTCACCGGTGCCCCCAAAACACGCTGGGAAGAAGCAGCCGCACGGGGGCCAGCAGAAGCCCTCCTACGGCTCGGGCTACCAGTCCCACCAGGGCCAGCAGCAGTCCTACAACCAGAGCCCCTACAGCAACTATGGCCCTCCACAGGGCAAGCAGAAAGGCTATAACCATGGACAAGGCAGCTACTCCTACTCGAACTCCTACAACTCTCCCGGGGGCGGGGGCGGATCCGACTACAACTACGAGAGCAAATTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000129351_CASSETTE5
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.052 A=0.000 C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAAGCTATGGGTACGGAGG
R:
TGGTAGTAGGAGCCATAGCCG
Band lengths:
138-199
Functional annotations
There are 1 annotated functions for this event
PMID: 31911676
This event
[CRISPR screen]. Conserved poison exon with pro-oncogenic impact when depleted: HeLa Enriched at 14 days (FC=1.278, FDR=0.002), PC9 No Change at 14 days (FC=0.979, FDR=0.749), Late Xenograft No change (FC=0.994, FDR=0.324).
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)