HsaEX0031555 @ hg38
Exon Skipping
Gene
ENSG00000129351 | ILF3
Description
interleukin enhancer binding factor 3 [Source:HGNC Symbol;Acc:HGNC:6038]
Coordinates
chr19:10683917-10687708:+
Coord C1 exon
chr19:10683917-10683970
Coord A exon
chr19:10684416-10684476
Coord C2 exon
chr19:10687346-10687708
Length
61 bp
Sequences
Splice sites
3' ss Seq
TCTGTCTCCCCCTTTTGTAGGTG
3' ss Score
11.91
5' ss Seq
AAAGTATTG
5' ss Score
-1.65
Exon sequences
Seq C1 exon
GTGCTGGGTATGGAAGCTATGGGTACGGAGGCAACTCGGCGACAGCAGGCTACA
Seq A exon
GTGACTTTTTCACAGACTGCTACGGCTATCATGATTTTGGGTCTTCCTAGAGCGTCTAAAA
Seq C2 exon
GTCAGTTCTACAGCAACGGAGGGCATTCTGGGAATGCCAGTGGCGGTGGCGGCGGGGGCGGTGGTGGCTCCTCCGGCTATGGCTCCTACTACCAAGGTGACAACTACAACTCACCGGTGCCCCCAAAACACGCTGGGAAGAAGCAGCCGCACGGGGGCCAGCAGAAGCCCTCCTACGGCTCGGGCTACCAGTCCCACCAGGGCCAGCAGCAGTCCTACAACCAGAGCCCCTACAGCAACTATGGCCCTCCACAGGGCAAGCAGAAAGGCTATAACCATGGACAAGGCAGCTACTCCTACTCGAACTCCTACAACTCTCCCGGGGGCGGGGGCGGATCCGACTACAACTACGAGAGCAAATTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000129351_MULTIEX1-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.039 A=0.000 C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAAGCTATGGGTACGGAGG
R:
TGGTAGTAGGAGCCATAGCCG
Band lengths:
138-199
Functional annotations
There are 1 annotated functions for this event
PMID: 31911676
[CRISPR screen]. Conserved poison exon with pro-oncogenic impact when depleted: HeLa Enriched at 14 days (FC=1.278, FDR=0.002), PC9 No Change at 14 days (FC=0.979, FDR=0.749), Late Xenograft No change (FC=0.994, FDR=0.324).
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development