HsaEX0032977 @ hg38
Exon Skipping
Gene
ENSG00000135519 | KCNH3
Description
potassium voltage-gated channel subfamily H member 3 [Source:HGNC Symbol;Acc:HGNC:6252]
Coordinates
chr12:49549441-49554554:+
Coord C1 exon
chr12:49549441-49549640
Coord A exon
chr12:49550080-49550329
Coord C2 exon
chr12:49554337-49554554
Length
250 bp
Sequences
Splice sites
3' ss Seq
CCGCACCTGCTCACCTGCAGCTG
3' ss Score
7.79
5' ss Seq
TAGGTTTGT
5' ss Score
4.07
Exon sequences
Seq C1 exon
CCCTGATGCACGCGGTGGTGTTTGGGAACGTGACGGCCATCATCCAGCGCATGTACGCCCGCCGCTTTCTGTACCACAGCCGCACGCGCGACCTGCGCGACTACATCCGCATCCACCGTATCCCCAAGCCCCTCAAGCAGCGCATGCTGGAGTACTTCCAGGCCACCTGGGCGGTGAACAATGGCATCGACACCACCGAG
Seq A exon
CTGCTGCAGAGCCTCCCTGACGAGCTGCGCGCAGACATCGCCATGCACCTGCACAAGGAGGTCCTGCAGCTGCCACTGTTTGAGGCGGCCAGCCGCGGCTGCCTGCGGGCACTGTCTCTGGCCCTGCGGCCCGCCTTCTGCACGCCGGGCGAGTACCTCATCCACCAAGGCGATGCCCTGCAGGCCCTCTACTTTGTCTGCTCTGGCTCCATGGAGGTGCTCAAGGGTGGCACCGTGCTCGCCATCCTAG
Seq C2 exon
GGAAGGGCGACCTGATCGGCTGTGAGCTGCCCCGGCGGGAGCAGGTGGTAAAGGCCAATGCCGACGTGAAGGGGCTGACGTACTGCGTCCTGCAGTGTCTGCAGCTGGCTGGCCTGCACGACAGCCTTGCGCTGTACCCCGAGTTTGCCCCGCGCTTCAGTCGTGGCCTCCGAGGGGAGCTCAGCTACAACCTGGGTGCTGGGGGAGGCTCTGCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135519_MULTIEX1-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.078
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PD(4.2=14.9)
A:
PF0002724=cNMP_binding=PU(45.5=47.6)
C2:
PF0002724=cNMP_binding=PD(53.4=64.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTACATCCGCATCCACCGTA
R:
ACCCAGGTTGTAGCTGAGCTC
Band lengths:
298-548
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development