HsaEX0035235 @ hg38
Exon Skipping
Gene
ENSG00000053747 | LAMA3
Description
laminin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6483]
Coordinates
chr18:23943788-23949924:+
Coord C1 exon
chr18:23943788-23943971
Coord A exon
chr18:23946144-23946284
Coord C2 exon
chr18:23949765-23949924
Length
141 bp
Sequences
Splice sites
3' ss Seq
GTATCTTTCTTACTCTGAAGGTG
3' ss Score
8.36
5' ss Seq
AAGGTAAAT
5' ss Score
8.88
Exon sequences
Seq C1 exon
GTCACAGTTTGCTGTGGACATGCAGACAACATCCTCCAGAGGACTGGTGTTTCACACGGGCACTAAGAACTCCTTTATGGCTCTTTATCTTTCAAAAGGACGTCTGGTCTTTGCACTGGGGACAGATGGGAAAAAATTGAGGATCAAAAGCAAGGAGAAATGCAATGATGGGAAATGGCACACG
Seq A exon
GTGGTGTTTGGCCATGATGGGGAAAAGGGGCGCTTGGTTGTGGATGGACTGAGGGCCCGGGAGGGAAGTTTGCCTGGAAACTCCACCATCAGCATCAGAGCGCCAGTTTACCTGGGATCACCTCCATCAGGGAAACCAAAG
Seq C2 exon
AGCCTCCCCACAAACAGCTTTGTGGGATGCCTGAAGAACTTTCAGCTGGATTCAAAACCCTTGTATACCCCTTCTTCAAGCTTCGGGGTGTCTTCCTGCTTGGGTGGTCCTTTGGAGAAAGGCATTTATTTCTCTGAAGAAGGAGGTCATGTCGTCTTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000053747-'129-128,'129-125,130-128
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.023 A=0.089 C2=0.000
Domain overlap (PFAM):
C1:
PF0221019=Laminin_G_2=PU(44.6=87.1)
A:
PF0221019=Laminin_G_2=FE(38.0=100)
C2:
PF0221019=Laminin_G_2=PD(14.9=33.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACACGGGCACTAAGAACTCC
R:
AAAGGACCACCCAAGCAGGAA
Band lengths:
245-386
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development