HsaEX0036899 @ hg38
Exon Skipping
Gene
ENSG00000119681 | LTBP2
Description
latent transforming growth factor beta binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6715]
Coordinates
chr14:74535926-74551350:-
Coord C1 exon
chr14:74551064-74551350
Coord A exon
chr14:74549863-74549965
Coord C2 exon
chr14:74535926-74536000
Length
103 bp
Sequences
Splice sites
3' ss Seq
TCCATGGCCTCTCCTTCCAGTGT
3' ss Score
9.13
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
CCTCCGTGAACCCCTCCCTGGTGAAGGTGCACATTCACCACCCACCCGAGGCCTCAGTGCAGATCCACCAGGTGGCCCAGGTGCGGGGCGGGGTGGAGGAGGCCCTAGTGGAGAACAGCGTGGAGACCAGACCCCCGCCCTGGCTGCCTGCCAGCCCTGGCCACAGCCTCTGGGACAGCAACAACATCCCTGCTCGGTCTGGAGAGCCCCCTCGGCCACTGCCCCCAGCAGCACCCAGGCCTCGAGGACTGCTGGGCCGGTGTTACCTGAACACTGTGAACGGACAG
Seq A exon
TGTGCCAACCCTCTGCTGGAGCTGACTACCCAGGAGGACTGCTGTGGCAGTGTGGGAGCCTTCTGGGGGGTGACTTTGTGTGCCCCATGCCCACCCAGACCAG
Seq C2 exon
CCTCCCCGGTGATTGAGAATGGCCAGCTGGAGTGTCCTCAGGGGTACAAGAGACTGAACCTCACTCACTGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119681-'27-24,'27-17,28-24
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.566 A=0.000 C2=0.015
Domain overlap (PFAM):
C1:
PF0068312=TB=PU(2.6=1.0)
A:
PF0068312=TB=FE(87.2=100)
C2:
PF0068312=TB=PD(5.1=7.7),PF0764510=EGF_CA=PU(0.1=0.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAGTGGAGAACAGCGTGGAGA
R:
TGGCAGTGAGTGAGGTTCAGT
Band lengths:
255-358
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development