HsaEX0037171 @ hg38
Exon Skipping
Gene
ENSG00000127603 | MACF1
Description
microtubule-actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]
Coordinates
chr1:39331203-39340717:+
Coord C1 exon
chr1:39331203-39336653
Coord A exon
chr1:39337182-39337331
Coord C2 exon
chr1:39340502-39340717
Length
150 bp
Sequences
Splice sites
3' ss Seq
CTTTCTTTTTGGCTCCACAGAAT
3' ss Score
10.41
5' ss Seq
AAGGTAGGT
5' ss Score
10.29
Exon sequences
Seq C1 exon
TCACAGTTTCTAGACCAGATTCAAAAGAAGTCAGGTATCTAGAATTCTCAGACAGAAAAGACCTTCATCATCAGGGCAGCAAAAGTGATGATAAACTTTGTGGAACTCTCAAATCTGAAATAGCAACACAGGAACTAACTGGAGAGAAATTTCTAGAAATGGCAAACCCTAATGTTGCAGGTCTAGAAGCAGGATCCATTGAGGACATAGTGACTCAGAGAGGTTCCAGAGTCTTGGGATCCTTTCTTCCAGAGAAACTGTTCAAAGGAGTGTCTCAAAAAGAGAATACAGGGCAACAGAATGCCATCATTAGTCCTACTGTTCTAGAGACCAGTGAAGAAAAGACAGTGTCCCTAACAGTATGCTCTGCAGTGAAGACAGAGAAGACACCACAGGAAAAGCTCAGAGAAAGCCCTGGCAGTGAACAAACTCCCTTCATGACTGCACCTGAAGGAAAGGGAAATGGAGGTGTAAACCCAGAGCCCTTCAGAGCAACTCAG
Seq A exon
AATGTATTTACCCGGCAACTCTGTTTAGAACATGATGAAAAGCTAGTATCCTATCTGTCTCTGTTACGGAACATTGAAATGAGGACCAAACAGATTCAACCTTTGGAGCTAAACCTGGCAGAACTACAGGATCTGCTGTGTCAGGCCAAG
Seq C2 exon
GTATTAGAAAGGGAGTTAAAGGATCTGACCACCTTGGTCAGTCAGGAGCTGGAGTGTGTGAATCAGATTATCATCAGCCAGCCTCAAGAAGTTCCTGCTCAACTGTTGAAGGCTCTAGAGAAAGATGCCAAGAATCTTCAGAAGTCTCTCAGCTCTGTGAGTGACACTTGGAATTCCAGGCTACTCCACTTCCAGAATGCTGTGGAAATAGAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000127603-'98-110,'98-109,99-110
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.282 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0068115=Plectin=WD(100=2.1),PF0068115=Plectin=WD(100=2.5),PF0068115=Plectin=WD(100=2.5),PF0068115=Plectin=WD(100=2.5),PF0068115=Plectin=WD(100=2.4),PF0068115=Plectin=WD(100=1.9),PF0068115=Plectin=WD(100=2.5),PF0068115=Plectin=WD(100=2.5),PF0068115=Plectin=WD(100=2.1),PF0068115=Plectin=WD(100=2.4),PF0068115=Plectin=WD(100=2.5),PF0068115=Plectin=WD(100=2.1),PF0068115=Plectin=WD(100=2.3),PF0068115=Plectin=WD(100=2.5)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACTGCACCTGAAGGAAAGGG
R:
CTGGAAGTGGAGTAGCCTGGA
Band lengths:
256-406
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development