HsaEX0038098 @ hg19
Exon Skipping
Gene
ENSG00000166987 | MBD6
Description
methyl-CpG binding domain protein 6 [Source:HGNC Symbol;Acc:20445]
Coordinates
chr12:57919131-57921443:+
Coord C1 exon
chr12:57919131-57920171
Coord A exon
chr12:57920349-57921010
Coord C2 exon
chr12:57921290-57921443
Length
662 bp
Sequences
Splice sites
3' ss Seq
ATTTCTCTCCTCTTTTACAGGTG
3' ss Score
13.2
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
CCCCACGGTGGAGGGGCCTGGGGCACCCCCCTTCCTTGCTAGCAGCCTACTCTCTGCAGCGGCCAAGGCACAGCATCCCCCACTACCCCCTCCCAGCACTTTACAGGGCCGAAGGCCCCGTGCCCAGGCACCCTCAGCTTCCCACTCCTCATCACTTCGTCCCTCTCAGCGTCGTCCCCGCAGACCCCCTACTGTATTTCGATTGCTAGAAGGGAGAGGCCCTCAAACCCCTAGACGGAGCCGTCCTCGGGCCCCTGCTCCTGTCCCCCAACCCTTTTCTCTCCCGGAGCCATCCCAACCAATTCTCCCTTCTGTGCTGTCCCTGCTGGGACTCCCCACCCCTGGCCCTTCCCACTCTGATGGAAGCTTTAACCTTTTGGGGTCAGATGCACACCTTCCTCCTCCCCCAACCCTCTCCTCAGGGAGCCCTCCCCAGCCCAGGCACCCCATCCAGCCCTCCCTGCCTGGGACCACCAGTGGCAGCCTCAGCAGTGTGCCAG
Seq A exon
GTGCCCCTGCCCCACCAGCTGCCTCCAAAGCCCCAGTAGTCCCCAGCCCTGTGCTTCAAAGCCCATCCGAAGGACTGGGGATGGGGGCAGGCCCGGCCTGCCCTCTGCCTCCCCTGGCTGGTGGAGAGGCTTTCCCTTTCCCCAGCCCTGAGCAGGGCCTGGCACTGAGTGGAGCTGGCTTCCCTGGGATGCTTGGGGCCTTGCCTCTCCCTCTGAGTCTGGGGCAGCCTCCACCTTCTCCATTGCTCAACCACAGTTTATTTGGTGTGCTGACTGGGGGAGGAGGACAACCTCCCCCTGAGCCCCTGCTACCCCCACCAGGAGGACCTGGTCCTCCCCTAGCCCCAGGAGAGCCTGAAGGGCCTTCGCTTTTGGTGGCTTCCTTGCTTCCTCCACCACCCTCAGACCTTCTTCCACCTCCTTCAGCACCTCCCAGCAACCTCCTTGCCTCTTTCCTGCCCCTGTTGGCTCTGGGCCCCACAGCTGGGGATGGGGAGGGATCTGCAGAGGGAGCCGGGGGTCCAAGTGGGGAGCCATTTTCAGGCTTGGGAGACCTGTCCCCCCTACTTTTCCCCCCACTTTCAGCCCCCCCTACCCTCATAGCTTTAAATTCTGCGCTGCTGGCTGCCACCCTGGATCCCCCCTCGGGGACACCCCCCCAG
Seq C2 exon
CCCTGTGTCCTGAGTGCCCCCCAACCTGGACCACCTACCTCCAGTGTCACCACGGCAACTACTGACCCGGGGGCCTCCTCTCTGGGCAAGGCCCCCTCCAACTCAGGGAGACCCCCCCAACTCCTTAGCCCTCTGCTGGGTGCCAGCCTGCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166987_MULTIEX1-2/3=1-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.986 A=0.900 C2=0.871
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCTCAAACCCCTAGACGGAG
R:
GTCAGTAGTTGCCGTGGTGAC
Band lengths:
347-1009
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)