HsaEX0038098 @ hg38
Exon Skipping
Gene
ENSG00000166987 | MBD6
Description
methyl-CpG binding domain protein 6 [Source:HGNC Symbol;Acc:HGNC:20445]
Coordinates
chr12:57525348-57527660:+
Coord C1 exon
chr12:57525348-57526388
Coord A exon
chr12:57526566-57527227
Coord C2 exon
chr12:57527507-57527660
Length
662 bp
Sequences
Splice sites
3' ss Seq
ATTTCTCTCCTCTTTTACAGGTG
3' ss Score
13.2
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
CCCCACGGTGGAGGGGCCTGGGGCACCCCCCTTCCTTGCTAGCAGCCTACTCTCTGCAGCGGCCAAGGCACAGCATCCCCCACTACCCCCTCCCAGCACTTTACAGGGCCGAAGGCCCCGTGCCCAGGCACCCTCAGCTTCCCACTCCTCATCACTTCGTCCCTCTCAGCGTCGTCCCCGCAGACCCCCTACTGTATTTCGATTGCTAGAAGGGAGAGGCCCTCAAACCCCTAGACGGAGCCGTCCTCGGGCCCCTGCTCCTGTCCCCCAACCCTTTTCTCTCCCGGAGCCATCCCAACCAATTCTCCCTTCTGTGCTGTCCCTGCTGGGACTCCCCACCCCTGGCCCTTCCCACTCTGATGGAAGCTTTAACCTTTTGGGGTCAGATGCACACCTTCCTCCTCCCCCAACCCTCTCCTCAGGGAGCCCTCCCCAGCCCAGGCACCCCATCCAGCCCTCCCTGCCTGGGACCACCAGTGGCAGCCTCAGCAGTGTGCCAG
Seq A exon
GTGCCCCTGCCCCACCAGCTGCCTCCAAAGCCCCAGTAGTCCCCAGCCCTGTGCTTCAAAGCCCATCCGAAGGACTGGGGATGGGGGCAGGCCCGGCCTGCCCTCTGCCTCCCCTGGCTGGTGGAGAGGCTTTCCCTTTCCCCAGCCCTGAGCAGGGCCTGGCACTGAGTGGAGCTGGCTTCCCTGGGATGCTTGGGGCCTTGCCTCTCCCTCTGAGTCTGGGGCAGCCTCCACCTTCTCCATTGCTCAACCACAGTTTATTTGGTGTGCTGACTGGGGGAGGAGGACAACCTCCCCCTGAGCCCCTGCTACCCCCACCAGGAGGACCTGGTCCTCCCCTAGCCCCAGGAGAGCCTGAAGGGCCTTCGCTTTTGGTGGCTTCCTTGCTTCCTCCACCACCCTCAGACCTTCTTCCACCTCCTTCAGCACCTCCCAGCAACCTCCTTGCCTCTTTCCTGCCCCTGTTGGCTCTGGGCCCCACAGCTGGGGATGGGGAGGGATCTGCAGAGGGAGCCGGGGGTCCAAGTGGGGAGCCATTTTCAGGCTTGGGAGACCTGTCCCCCCTACTTTTCCCCCCACTTTCAGCCCCCCCTACCCTCATAGCTTTAAATTCTGCGCTGCTGGCTGCCACCCTGGATCCCCCCTCGGGGACACCCCCCCAG
Seq C2 exon
CCCTGTGTCCTGAGTGCCCCCCAACCTGGACCACCTACCTCCAGTGTCACCACGGCAACTACTGACCCGGGGGCCTCCTCTCTGGGCAAGGCCCCCTCCAACTCAGGGAGACCCCCCCAACTCCTTAGCCCTCTGCTGGGTGCCAGCCTGCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166987-'19-27,'19-23,21-27
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.987 A=0.899 C2=0.942
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCTCAAACCCCTAGACGGAG
R:
GTCAGTAGTTGCCGTGGTGAC
Band lengths:
347-1009
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development