HsaEX0038745 @ hg38
Exon Skipping
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3515402-3531448:-
Coord C1 exon
chr1:3531080-3531448
Coord A exon
chr1:3524124-3524246
Coord C2 exon
chr1:3515402-3515527
Length
123 bp
Sequences
Splice sites
3' ss Seq
CCTTCCCCATTCCTGCTCAGATG
3' ss Score
8.18
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
Exon sequences
Seq C1 exon
GAGAACTTAAAGGCGAGGGGCGGGGCGCGCCCGGCCCAGAGCGGCTCCCGGGCGGCGCCGAGCGGAGCGGATCCCGGGGCTGGGATTGCGCGCCCGCCCGGAACCCAGAACCAGCCCGAGCCGCCTGCCCCGTCGCCCGGCCGCCGGCTTAGGGCGCAGCGCGGTTGGTCCTCGCCCCCTCCCGCCCGCCGGCCTACCAGGCCATGGGGGCGTCCCGGGACCGCGGGCTGGCCGCGCTCTGGTGCCTTGGGCTCCTGGGGGGCCTGGCGCGCGTCGCGGGCACGCACTACCGCTACCTCTGGAGGGGCTGCTACCCATGTCACCTGGGCCAGGCCGGCTACCCCGTGAGCGCCGGTGACCAGAGGCCAG
Seq A exon
ATGTGGACGAATGCCGAACCCACAACGGTGGCTGCCAGCACCGGTGCGTGAACACCCCAGGCTCCTACCTCTGTGAGTGCAAGCCCGGCTTCCGGCTCCACACTGACAGCAGGACCTGCCTGG
Seq C2 exon
CCATTAACTCCTGCGCCCTGGGCAATGGCGGCTGCCAGCACCACTGTGTCCAGCTCACAATCACTCGGCATCGCTGCCAGTGCCGGCCCGGGTTCCAGCTCCAGGAGGACGGCAGGCATTGTGTCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591-'13-20,'13-17,19-20
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.062 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF146701=FXa_inhibition=WD(100=85.7)
C2:
PF146701=FXa_inhibition=WD(100=86.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTGGTCCTCGCCCCCTC
R:
TTGTGAGCTGGACACAGTGGT
Band lengths:
266-389
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development