HsaEX0039530 @ hg19
Exon Skipping
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 [Source:HGNC Symbol;Acc:16063]
Coordinates
chr10:21813604-21827841:+
Coord C1 exon
chr10:21813604-21813704
Coord A exon
chr10:21823574-21823733
Coord C2 exon
chr10:21827762-21827841
Length
160 bp
Sequences
Splice sites
3' ss Seq
TCCCCCCAACTCCCTCTTAGATG
3' ss Score
7.16
5' ss Seq
AAGGTAAAC
5' ss Score
8.14
Exon sequences
Seq C1 exon
TGGAATACAAACTCTCCCGACATCCGTAGTTACTTTCAAGGTGGATTGTGTATTTTAAGGCTGATGGGAACGTCTGGTTTGTGGAGCAAAAAGAAGAGAAG
Seq A exon
ATGGTCTCTAGCGACCGGCCCGTGTCACTGGAGGACGAGGTCTCCCATAGTATGAAGGAGATGATTGGAGGCTGTTGCGTTTGCTCAGACGAGAGAGGCTGGGCCGAGAACCCGCTGGTTTATTGCGACGGGCACGGCTGCAGCGTCGCGGTGCATCAAG
Seq C2 exon
CTTGCTATGGCATTGTTCAAGTACCCACTGGACCGTGGTTTTGCAGGAAATGTGAATCTCAGGAGAGAGCAGCCAGAGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403-'0-3,'0-0,3-3
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.047 C2=0.000
Domain overlap (PFAM):
C1:
NA
A:
PF138311=PHD_2=PU(48.6=33.3)
C2:
PF138311=PHD_2=PD(48.6=66.7),PF138321=zf-HC5HC2H_2=PU(0.1=0.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
ENSP00000307411f1253A, ENSP00000366258, ENSP00000366272, ENSP00000366272f10360A, ENSP00000366272f10361A, ENSP00000366272f11426A, ENSP00000366272f1248A, ENSP00000366272f1249A, ENSP00000366272f1250A, ENSP00000366272f1251A, ENSP00000366272f1252A, ENSP00000366295, ENSP00000366304, ENSP00000397800, ENSP00000401406
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAATACAAACTCTCCCGACA
R:
CTCTGGCTGCTCTCTCCTGAG
Band lengths:
179-339
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)