HsaEX0040458 @ hg19
Exon Skipping
Gene
ENSG00000143033 | MTF2
Description
metal response element binding transcription factor 2 [Source:HGNC Symbol;Acc:29535]
Coordinates
chr1:93544795-93580340:+
Coord C1 exon
chr1:93544795-93545088
Coord A exon
chr1:93575884-93575985
Coord C2 exon
chr1:93580245-93580340
Length
102 bp
Sequences
Splice sites
3' ss Seq
TGACCAAGCTGTCTTTACAGGAT
3' ss Score
6.87
5' ss Seq
AAGGCAAGT
5' ss Score
3.24
Exon sequences
Seq C1 exon
GCCATTCGGCACCGGAGTCGCTCCGCGCTCCCAGAATGCACCGGCAGTCCGCGGGAAACCAAAATGGCGAGGGGCTGTATTGAAGTGGGCTGTGTTTGAGGCCGGTGTAAGAACGCTCATTCTACCCCCAACCCTTGTCTCCAAGGACCTCGGTTTGTGCGTGCATATGTGCCGGGTACCCGGTGGGGCGGGTGCCCAGTAAGTGCTCGGACTCGCAGGGGAAGCGCCCACGGGGACGGATTGGTTGTTTTTTCCTGTATGAAGCGGTTGGCACCACTGAAGTGACCGAATGAG
Seq A exon
GATGGACATAAAGCCAAAAAGCCAGCATGTAAATTTGAAGAGGGTCAGGATGTCCTAGCTAGATGGTCAGATGGCTTGTTTTATCTTGGCACTATCAAAAAG
Seq C2 exon
GAGCCACTGGAAGTGGGGAAATGGTCTGTACAATATGTCAAGAAGAGTATTCAGAAGCTCCCAATGAAATGGTTATATGTGACAAGTGTGGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000143033_MULTIEX1-3/4=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
Show structural model
Features
Disorder rate (Iupred):
C1=0.312 A=0.343 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF150571=DUF4537=PU(31.1=28.4)
C2:
PF150571=DUF4537=PD(23.8=45.5),PF0013017=C1_1=FE(61.5=100),PF144461=Prok-RING_1=PU(50.0=84.8),PF0062824=PHD=PU(44.4=72.7)
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAAGTGGGCTGTGTTTGAGG
R:
CAGACCATTTCCCCACTTCCA
Band lengths:
242-344
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)