HsaEX0040965 @ hg38

Exon Skipping

Gene

ENSG00000144821 | MYH15

Description

myosin heavy chain 15 [Source:HGNC Symbol;Acc:HGNC:31073]

Coordinates

chr3:108430832-108439913:-

Coord C1 exon

chr3:108439737-108439913

Coord A exon

chr3:108437554-108437699

Coord C2 exon

chr3:108430832-108430922

Length

146 bp

Sequences

Splice sites

3' ss Seq

ATAATGTTTCCTTTTGTCAGCTT

3' ss Score

6.16

5' ss Seq

GAAGTAAGC

5' ss Score

6.95

Exon sequences

Seq C1 exon

GTCAAGAACTTGACTGAGGAAGTAGAGTTTCTAAATGAGGATATCAGCAAACTTAACAGAGCAGCCAAGGTTGTGCAGGAGGCCCATCAGCAGACCCTGGATGACCTGCACATGGAGGAGGAGAAGCTCAGCAGCCTGAGCAAAGCAAATCTGAAGCTGGAACAGCAAGTTGATGAG

Seq A exon

CTTGAGGGTGCCCTTGAGCAGGAGAGAAAAGCGAGAATGAACTGTGAAAGGGAACTGCACAAACTGGAGGGCAATTTAAAGCTGAATCGGGAAAGTATGGAGAACCTGGAAAGCAGCCAGCGACACCTGGCAGAAGAGCTGAGGAA

Seq C2 exon

AAAAGAATTAGAATTGAGTCAGATGAATTCAAAAGTGGAGAATGAGAAAGGCCTGGTAGCTCAGCTTCAGAAGACGGTTAAAGAGCTTCAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000144821_CASSETTE5

Average complexity

S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.508 A=0.980 C2=0.677

Domain overlap (PFAM):

C1:

PF0157614=Myosin_tail_1=FE(25.3=100),PF131661=AAA_13=FE(24.0=100),PF045827=Reo_sigmaC=PU(23.9=54.2),PF087025=Fib_alpha=PU(15.7=30.5)

A:

PF0157614=Myosin_tail_1=PD(15.3=71.4),PF131661=AAA_13=FE(19.8=100),PF087025=Fib_alpha=FE(41.7=100),PF045827=Reo_sigmaC=PU(30.4=77.6),PF0157614=Myosin_tail_1=PU(2.7=28.6)

C2:

PF131661=AAA_13=FE(12.4=100),PF045827=Reo_sigmaC=FE(22.4=100),PF087025=Fib_alpha=FE(26.1=100),PF0157614=Myosin_tail_1=FE(3.5=100)

Main Inclusion Isoform:

ENSP00000273353