HsaEX0042626 @ hg38
Exon Skipping
Gene
ENSG00000162614 | NEXN
Description
nexilin F-actin binding protein [Source:HGNC Symbol;Acc:HGNC:29557]
Coordinates
chr1:77918125-77929504:+
Coord C1 exon
chr1:77918125-77918273
Coord A exon
chr1:77926716-77926892
Coord C2 exon
chr1:77929316-77929504
Length
177 bp
Sequences
Splice sites
3' ss Seq
TTTTCATAACGTTTTCTTAGGAT
3' ss Score
7.94
5' ss Seq
ATGGTAAAT
5' ss Score
6.41
Exon sequences
Seq C1 exon
GAACTGTGAAGGGTAGATTTGCTGAAATGGAGAAACAAAGACAAGAGGAACAAAGGAAGAGAACGGAGGAGGAACGAAAACGCAGAATTGAGCAGGATATGTTAGAAAAGAGGAAAATACAGCGTGAATTAGCAAAAAGGGCTGAACAG
Seq A exon
GATGATGAAATAGAAAGTGAAGCAAAAAAAGAATCACTTTCTCCCGGAAAATTGAAACTAACTTTTGAAGAACTGGAGCGACAAAGACAAGAAAACCGAAAGAAGCAAGCTGAAGAGGAAGCAAGAAAACGTTTAGAAGAAGAGAAGCGTGCTTTTGAAGAAGCAAGGCGGCAAATG
Seq C2 exon
GTAAATGAAGATGAGGAAAACCAAGACACAGCAAAAATTTTTAAAGGGTACCGCCCTGGTAAACTCAAACTCAGTTTTGAAGAAATGGAAAGGCAAAGAAGAGAAGATGAAAAAAGGAAAGCAGAAGAAGAAGCCAGAAGGAGAATAGAGGAAGAAAAGAAGGCGTTTGCTGAAGCAAGGAGAAATATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162614_MULTIEX3-4/4=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.909 A=0.949 C2=0.813
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
ENST00000334785fB21040
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGAAAACGCAGAATTGAGCAGG
R:
GCTTCAGCAAACGCCTTCTTT
Band lengths:
251-428
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development