HsaEX0042628 @ hg19
Exon Skipping
Gene
ENSG00000162614 | NEXN
Description
nexilin (F actin binding protein) [Source:HGNC Symbol;Acc:29557]
Coordinates
chr1:78398967-78407893:+
Coord C1 exon
chr1:78398967-78399164
Coord A exon
chr1:78401508-78401729
Coord C2 exon
chr1:78407708-78407893
Length
222 bp
Sequences
Splice sites
3' ss Seq
CTTATTAATTTTTTTTGAAGGAA
3' ss Score
6.55
5' ss Seq
GAGGTATAT
5' ss Score
7.3
Exon sequences
Seq C1 exon
GTAGTAGATGATGACTCCCCAGAGATGTATAAGACAATCTCTCAAGAATTTCTTACACCGGGAAAACTGGAAATTAATTTTGAAGAATTATTAAAACAAAAAATGGAAGAAGAAAAACGACGAACAGAGGAGGAACGGAAGCATAAGCTAGAAATGGAGAAACAAGAATTTGAACAACTGAGACAGGAAATGGGAGAG
Seq A exon
GAAGAGGAAGAAAATGAAACCTTTGGATTGAGCAGAGAATATGAAGAACTGATCAAATTAAAAAGGAGTGGCTCTATTCAAGCTAAAAACCTAAAAAGCAAGTTTGAAAAAATTGGACAGTTGTCTGAAAAAGAAATACAGAAAAAAATAGAAGAAGAGCGAGCAAGAAGGAGAGCAATTGACCTTGAAATTAAAGAGCGAGAAGCTGAAAATTTTCATGAG
Seq C2 exon
GAAGATGATGTTGATGTTAGGCCTGCAAGAAAAAGCGAGGCTCCATTTACTCACAAAGTGAATATGAAAGCTAGATTTGAACAAATGGCTAAGGCAAGAGAAGAAGAAGAACAAAGAAGAATTGAAGAACAAAAGTTACTACGCATGCAGTTTGAACAAAGGGAAATTGATGCAGCACTACAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162614_MULTIEX2-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.780 A=0.392 C2=0.818
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGATGATGACTCCCCAGAGATGT
R:
TCTTCTTCTCTTGCCTTAGCCA
Band lengths:
300-522
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)