HsaEX0046393 @ hg19
Exon Skipping
Gene
ENSG00000152256 | PDK1
Description
pyruvate dehydrogenase kinase, isozyme 1 [Source:HGNC Symbol;Acc:8809]
Coordinates
chr2:173431584-173435552:+
Coord C1 exon
chr2:173431584-173431661
Coord A exon
chr2:173433469-173433545
Coord C2 exon
chr2:173435454-173435552
Length
77 bp
Sequences
Splice sites
3' ss Seq
TTTTCTCTTCTGCTCTGTAGCAA
3' ss Score
8
5' ss Seq
AAGGTTTGT
5' ss Score
7.81
Exon sequences
Seq C1 exon
ATGGCTATGAAAATGCTAGGCGTCTGTGTGATTTGTATTATATTAACTCTCCCGAACTAGAACTTGAAGAACTAAATG
Seq A exon
CAAAATCACCAGGACAGCCAATACAAGTGGTTTATGTACCATCCCATCTCTATCACATGGTGTTTGAACTTTTCAAG
Seq C2 exon
AATGCAATGAGAGCCACTATGGAACACCATGCCAACAGAGGTGTTTACCCCCCTATTCAAGTTCATGTCACGCTGGGTAATGAGGATTTGACTGTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000152256_MULTIEX4-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.046 A=0.000 C2=0.008
Domain overlap (PFAM):
C1:
NO
A:
PF0251821=HATPase_c=PU(11.2=53.8)
C2:
PF0251821=HATPase_c=FE(25.6=100)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCTATGAAAATGCTAGGCGT
R:
GTCAAATCCTCATTACCCAGCGT
Band lengths:
169-246
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)