HsaEX0047507 @ hg19
Exon Skipping
Gene
ENSG00000011405 | PIK3C2A
Description
phosphoinositide-3-kinase, class 2, alpha polypeptide [Source:HGNC Symbol;Acc:8971]
Coordinates
chr11:17169064-17172202:-
Coord C1 exon
chr11:17172045-17172202
Coord A exon
chr11:17170214-17170334
Coord C2 exon
chr11:17169064-17169175
Length
121 bp
Sequences
Splice sites
3' ss Seq
AATGACTAACTCTTTTACAGTGA
3' ss Score
6
5' ss Seq
GAAGTAAGT
5' ss Score
9.82
Exon sequences
Seq C1 exon
ATTGAAGACCAAATTTCCATATACCAATCACCGCACAAACCCAGGCTATTTGTTAAGTCCAGTCACAGCACAAAGAAACATATGCGGAGAAAATGCTAGTGTGAAGGTCTCCATTGACATTGAAGGATTTCAGCTACCAGTTACTTTTACGTGTGATG
Seq A exon
TGAGTTCTACTGTAGAAATCATTATAATGCAAGCCCTTTGCTGGGTACATGATGACTTGAATCAAGTAGATGTTGGCAGCTATGTTCTAAAAGTTTGTGGTCAAGAGGAAGTGCTGCAGAA
Seq C2 exon
TAATCATTGCCTTGGAAGTCATGAGCATATTCAAAACTGTCGAAAATGGGACACAGAAATTAGACTACAACTCTTGACCTTCAGTGCAATGTGTCAAAATCTGGCCCGAACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000011405-'2-4,'2-3,3-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0079413=PI3K_rbd=PU(32.7=63.0)
A:
PF0079413=PI3K_rbd=FE(38.5=100)
C2:
PF0079413=PI3K_rbd=PD(27.9=76.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACCAATCACCGCACAAACCC
R:
TTCGGGCCAGATTTTGACACA
Band lengths:
247-368
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)