HsaEX0055740 @ hg19
Exon Skipping
Gene
ENSG00000124782 | RREB1
Description
ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:10449]
Coordinates
chr6:7226700-7240835:+
Coord C1 exon
chr6:7226700-7226889
Coord A exon
chr6:7229230-7232140
Coord C2 exon
chr6:7240671-7240835
Length
2911 bp
Sequences
Splice sites
3' ss Seq
TACCGGTGGGTTCTATATAGGCC
3' ss Score
5.73
5' ss Seq
CTGGTAAGA
5' ss Score
9.45
Exon sequences
Seq C1 exon
ATGTGACATTTGTTGTGTCACCTTTCGAACACATCGAGGACTGCTGCGTCACAACGCGCTTGTCCACAAACAACTTCCCAGGGATGCAATGGGCAGACCTTTCATACAGAACAACCCTTCAATTCCTGCTGGCTTCCACGACTTAGGATTCACGGACTTCTCCTGTAGGAAGTTTCCTCGCATTTCTCAG
Seq A exon
GCCTGGTGCGAAACAAACCTGCGGAGGTGCATCAGCGAGCAACACCGTTTTGTCTGCGACACCTGTGACAAGGCGTTCCCCATGCTCTGCTCACTGGCTCTGCACAAGCAGACCCATGTGGCGGCAGACCAGGGTCAAGAAAAGCCGCAGGCCACGCCCCTGCCTGGTGACGCCCTGGACCAGAAGGGCTTCCTGGCCTTGCTTGGCCTGCAGCACACCAAAGACGTCAGGCCTGCCCCCGCCGAGGAGCCCCTGCCGGATGACAACCAGGCAATTCAGCTCCAGACACTCAAGTGTCAGCTACCTCAGGACCCCGGCTGCACCAACCTGCTGAGCCTGTCACCTTTCGAAGCTGCTTCCCTAGGCGGTTCTCTCACAGTTCTCCCCGCGACCAAGGACAGCATAAAGCACCTGTCCCTGCAGCCCTTCCAGAAGGGCTTCATCATCCAGCCTGACAGCAGCATTGTGGTCAAGCCCATCTCTGGCGAGTCGGCCATCGAGCTGGCAGACATCCAGCAAATTCTGAAGATGGCAGCCTCGGCTCCCCCTCAGATCAGTCTTCCGCCCTTCTCCAAGGCCCCTGCCGCCCCACTGCAGGCGATCTTCAAGCACATGCCCCCTCTGAAGCCAAAGCCCCTGGTCACACCACGGACGGTGGTGGCCACCTCCACGCCCCCGCCTCTCATCAACGCCCAGCAGGCTTCCCCGGGCTGTATCAGCCCCAGCCTGCCGCCACCGCCCCTGAAGCTCCTCAAAGGCTCAGTGGAGGCGGCCTCCAACGCCCACCTGCTGCAGTCCAAGTCCGGGACCCAGCCCCACGCGGCCACGCGGCTCTCCCTGCAGCAGCCGCGGGCGGAGCTGCCGGGCCAGCCTGAGATGAAGACGCAGCTGGAGCAGGACAGCATCATCGAGGCCCTGCTGCCGCTGAGCATGGAGGCCAAGATCAAGCAGGAGATCACAGAGGGGGAACTCAAGGCCTTCATGACAGCGCCCGGCGGCAAGAAGACGCCCGCCATGCGCAAGGTGCTCTACCCCTGCCGCTTCTGCAACCAGGTGTTTGCCTTCTCGGGGGTCTTGCGTGCCCACGTGCGCTCCCACCTGGGCATCTCGCCATACCAGTGCAACATCTGCGACTACATCGCCGCCGACAAGGCCGCGCTCATCCGCCACCTGCGCACGCACAGTGGGGAGCGGCCCTACATTTGCAAGATCTGCCACTACCCCTTCACTGTCAAAGCCAACTGCGAGCGGCACCTGCGCAAGAAGCACCTCAAGGCCACCCGCAAGGATATCGAGAAGAACATCGAGTATGTGAGTAGCAGCGCGGCCGAGCTGGTGGACGCCTTCTGCGCCCCGGACACCGTGTGCCGGCTGTGCGGCGAGGACCTCAAGCACTATCGTGCCCTGCGCATCCACATGCGCACGCACTGCGGCCGCGGCCTGGGCGGGGGCCACAAGGGCCGCAAGCCCTTCGAGTGCAAGGAGTGCAGCGCCGCGTTCGCGGCCAAGCGCAACTGCATCCACCACATCCTCAAGCAGCACCTGCACGTGCCCGAGCAGGACATCGAGAGCTACGTGCTGGCCGCCGACGGCCTGGGCCCCGCAGAGGCGCCGGCCGCTGAGGCGTCGGGGCGCGGGGAGGACAGTGGCTGCGCTGCCCTTGGTGACTGCAAGCCCCTCACTGCCTTCCTGGAACCCCAGAACGGCTTTCTTCACAGGGGCCCCACCCAGCCTCCACCTCCCCATGTCTCGATCAAGTTGGAGCCCGCCAGTAGCTTTGCGGTGGACTTCAATGAGCCCCTGGACTTCTCGCAGAAGGGCCTGGCCCTGGTCCAAGTGAAGCAGGAAAACATCTCCTTTCTGAGCCCTTCTTCCCTGGTCCCCTATGACTGCTCCATGGAGCCCATCGACCTGTCCATCCCCAAGAACTTCAGGAAAGGGGACAAGGATTTGGCCACTCCCAGCGAAGCCAAGAAGCCTGAGGAGGAGGCGGGGAGCAGCGAGCAGCCCTCTCCCTGCCCAGCACCCGGCCCTTCTCTTCCTGTAACTTTGGGGCCCAGCGGAATCCTGGAAAGCCCCATGGCCCCTGCTCCGGCGGCCACCCCGGAACCCCCAGCACAGCCCCTGCAGGGCCCTGTTCAGCTGGCGGTCCCAATCTACTCCTCAGCCCTGGTCAGCAGCCCTCCACTCGTGGGCAGCTCAGCCCTCCTGAGTGGCACAGCCTTGCTGCGTCCACTGCGGCCCAAGCCCCCGCTGCTTTTGCCAAAGCCCCCCGTGACAGAAGAGCTGCCCCCGCTGGCCTCCATTGCCCAGATCATCTCATCTGTATCCTCGGCCCCCACCCTGCTGAAAACCAAGGTGGCGGACCCAGGGCCCGCAAGCACTGGCAGTAACACCACGGCTTCAGACAGCTTAGGAGGTTCTGTCCCCAAAGCCGCCACCACCGCCACCCCCGCTGCCACCACCAGCCCAAAAGAGTCTAGTGAGCCTCCCGCTCCAGCCAGCAGCCCAGAGGCTGCCTCTCCCACCGAGCAGGGCCCAGCGGGCACGTCGAAGAAGAGGGGCCGGAAAAGGGGGATGAGGAGCCGACCCCGCGCCAACAGCGGCGGGGTGGACCTGGACTCCAGCGGGGAGTTTGCCAGCATCGAGAAGATGCTGGCCACCACAGACACCAACAAGTTCAGTCCGTTTCTGCAGACAGCGGAGGACAACACTCAGGATGAGGTGGCCGGAGCCCCTGCCGACCACCATGGGCCCAGTGATGAAGAGCAGGGCAGTCCCCCAGAAGACAAGCTGCTGAGGGCCAAGCGGAACTCGTACACCAACTGCCTGCAGAAGATCACCTGTCCCCACTGTCCCCGGGTTTTCCCTTGGGCCAGCTCCCTACAGAGGCACATGCTCACACACACTG
Seq C2 exon
GTCAGAAACCCTTCCCTTGTCAAAAATGCGATGCCTTCTTTTCTACCAAATCTAACTGTGAACGCCACCAGTTGCGCAAACACGGAGTTACCACCTGTTCCCTGAGAAGAAACGGGCTTATCCCCCAGTCAAAAGAGAGTGATGTTGGATCCCATGATAGCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124782_MULTIEX2-2/5=1-3
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.109 A=0.427 C2=0.500
Domain overlap (PFAM):
C1:
NO
A:
PF134651=zf-H2C2_2=WD(100=2.6),PF134651=zf-H2C2_2=WD(100=2.7),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=PU(38.5=1.0)
C2:
PF134651=zf-H2C2_2=PD(57.7=26.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)