HsaEX0066767 @ hg19
Exon Skipping
Gene
ENSG00000132958 | TPTE2
Description
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:17299]
Coordinates
chr13:19997017-20000657:-
Coord C1 exon
chr13:20000565-20000657
Coord A exon
chr13:19999087-19999157
Coord C2 exon
chr13:19997017-19997304
Length
71 bp
Sequences
Splice sites
3' ss Seq
GAAATTTTTTTTCTTTTTAGAAT
3' ss Score
9.37
5' ss Seq
CAGGTATGA
5' ss Score
9.46
Exon sequences
Seq C1 exon
ATATTGCATGACATTGAAACAGACAAAATATTAATTAATGTATATGACGGTCCACCTCTGTATGATGATGTGAAAGTGCAGTTTTTCTCTTCG
Seq A exon
AATCTTCCTAAATACTATGACAATTGTCCATTTTTCTTCTGGTTCAACACGTCTTTTATTCAAAATAACAG
Seq C2 exon
GCTTTGTCTACCAAGAAATGAATTGGATAATCCACATAAACAAAAAGCATGGAAAATTTATCCACCAGAATTTGCTGTGGAGATACTTTTTGGCGAGAAATGACTTCCAATGATGTTGTAGCTGGATCCGACTAAGTATAGCTCCCCCTTCCCCTTCTGGGAAAGAATTATGTTCTTTCCAACCCCTGCCACATGTTCATGTGTCCTAAGTCTTCCTTGATGATGCATCTATATTTATATATGTTTATATATGTTCTTCATAAATCTATTAAATATATATAGATAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000132958-'20-26,'20-25,24-26
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF104094=PTEN_C2=FE(22.9=100)
A:
PF104094=PTEN_C2=FE(17.6=100)
C2:
PF104094=PTEN_C2=PD(24.4=91.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGACGGTCCACCTCTGTATGA
R:
GTCGGATCCAGCTACAACATCA
Band lengths:
181-252
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)