HsaEX0070594 @ hg38
Exon Skipping
Gene
ENSG00000176428 | VPS37D
Description
VPS37D, ESCRT-I subunit [Source:HGNC Symbol;Acc:HGNC:18287]
Coordinates
chr7:73669419-73672110:+
Coord C1 exon
chr7:73669419-73669590
Coord A exon
chr7:73670020-73670102
Coord C2 exon
chr7:73671014-73672110
Length
83 bp
Sequences
Splice sites
3' ss Seq
TGTCCCTCTGTGGCCCTCAGAGG
3' ss Score
8.79
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
Exon sequences
Seq C1 exon
TTCCAGGGCCTGCAGCTGGAGCGTGAGGCCTGCCTGGCCTCCAACTACGCGCTGGCCAAGGAGAACCTGGCCCTGCGGCCCCGCCTGGAGATGGGCCGGGCTGCCCTGGCCATCAAATACCAGGAGCTTCGTGAGGTGGCCGAGAACTGCGCGGACAAGCTGCAGCGACTGG
Seq A exon
AGGAAAGCATGCATCGCTGGAGTCCCCACTGCGCGCTGGGCTGGCTGCAGGCTGAGCTAGAAGAGGCGGAGCAGGAGGCAGAG
Seq C2 exon
GAGCAGATGGAGCAGCTGCTGCTCGGGGAGCAAAGCCTGGAGGCCTTCCTGCCTGCCTTCCAGCGTGGCCGCGCCCTGGCCCACCTGAGGCGGACGCAGGCAGAGAAGCTGCAGGAGCTGCTGCGGCGTCGGGAGCGTTCTGCCCAGCCGGCCCCCACCTCGGCTGCTGATCCCCCCAAATCCTTCCCGGCTGCAGCTGTCCTGCCCACTGGGGCCGCCCGGGGGCCACCAGCAGTGCCCCGGAGCCTGCCCCCCTTGGACTCCCGCCCAGTGCCCCCACTGAAGGGCTCCCCCGGGTGCCCCCTCGGCCCGGCCCCCCTGCTGAGCCCTCGGCCCTCGCAGCCAGAGCCCCCCCACCGGTAGGATCCACGGTGCGGCCCCCCAGTTGGGGGGCCTAGACAAACTTGATGCGTGGCTCCTCCTCCTCCCCCACTGCCTGGGTGGGGGGAGGGGCAGGCCCCTCCCCCTGGCCTCAGGCAGGCCCTGGCCCTGGAGGCTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000176428-'6-4,'6-2,8-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.017 A=0.143 C2=0.823
Domain overlap (PFAM):
C1:
PF072008=Mod_r=FE(38.0=100),PF0307011=TENA_THI-4=FE(38.8=100)
A:
PF072008=Mod_r=FE(18.0=100),PF0307011=TENA_THI-4=FE(18.4=100)
C2:
PF072008=Mod_r=PD(24.0=29.8),PF0307011=TENA_THI-4=PD(27.2=33.1)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCTGGCCATCAAATACCAG
R:
CAGCTTCTCTGCCTGCGTC
Band lengths:
181-264
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development