Special

HsaEX0073504 @ hg19

Exon Skipping

Gene
ENSG00000169981 | ZNF35
Description
zinc finger protein 35 [Source:HGNC Symbol;Acc:13099]
Coordinates
chr3:44692433-44702281:+
Coord C1 exon
chr3:44692433-44692751
Coord A exon
chr3:44694049-44694193
Coord C2 exon
chr3:44700193-44702281
Length
145 bp
Sequences
Splice sites
3' ss Seq
ATGTGCCTGCTTGTCTCTAGGGT
3' ss Score
9.92
5' ss Seq
TAGGTATGG
5' ss Score
7.37
Exon sequences
Seq C1 exon
TAGGCAGTACTCATCTTGGCCCTGGGAAGAAACTCAAGAAGAAGCTTTTGAAACATAAAGCTTGGATGGGGTTTGACCTCTGCAGGGCAGCGCCCAGCTATAGGAGTTCCCCTGCTGAGCAGAGAAGATGACTGCAGAATTGAGAGAAGCCATGGCCCTAGCCCCATGGGGCCCAGTGAAGGTGAAAAAGGAGGAGGAAGAAGAAGAAAACTTCCCAGGTCAGGCATCCAGCCAACAAGTGCACTCCGAGAACATCAAAGTCTGGGCCCCAGTGCAGGGTCTTCAGACAGGCCTTGATGGATCAGAAGAGGAAGAAAAG
Seq A exon
GGTCAGAACATATCCTGGGATATGGCGGTAGTCCTGAAAGCAACTCAGGAGGCACCTGCTGCTTCAACCCTTGGCAGCTACTCATTACCAGGGACTCTGGCCAAGAGTGAGATACTGGAGACTCATGGGACCATGAACTTTCTAG
Seq C2 exon
GTGCTGAAACCAAGAACCTACAGTTACTGGTTCCAAAAACTGAGATATGTGAGGAAGCTGAAAAACCCCTCATCATATCAGAAAGAATCCAGAAAGCTGATCCTCAAGGACCTGAGTTAGGAGAAGCTTGTGAAAAGGGAAACATGTTAAAGAGGCAGAGAATAAAGAGAGAAAAGAAAGATTTCAGACAAGTGATAGTGAATGACTGTCACTTACCTGAAAGCTTCAAAGAAGAGGAAAACCAGAAATGTAAGAAATCTGGAGGAAAATATAGCCTTAATTCTGGCGCTGTTAAAAATCCAAAAACCCAGCTTGGACAAAAGCCTTTTACGTGTAGCGTGTGTGGGAAAGGATTTAGTCAGAGTGCAAACCTCGTTGTGCATCAGCGAATCCACACTGGAGAGAAACCCTTTGAATGTCATGAGTGTGGGAAGGCCTTCATTCAGAGTGCAAACCTCGTTGTGCATCAGAGAATCCACACTGGACAGAAACCTTATGTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169981_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.533 A=0.342 C2=0.064
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
PF134651=zf-H2C2_2=WD(100=4.8),PF134651=zf-H2C2_2=WD(100=6.2),PF134651=zf-H2C2_2=WD(100=6.2),PF127602=Zn_Tnp_IS1595=WD(100=12.0),PF0009621=zf-C2H2=WD(100=5.5),PF0009621=zf-C2H2=WD(100=5.5),PF097235=Zn-ribbon_8=WD(100=10.3),PF134651=zf-H2C2_2=WD(100=6.2),PF134651=zf-H2C2_2=WD(100=6.2),PF134651=zf-H2C2_2=WD(100=6.0),PF134651=zf-H2C2_2=WD(100=6.2),PF134651=zf-H2C2_2=WD(100=6.2)

						

					

				








    
Main Inclusion Isoform:
ENSP00000379368





     
                   









    
Main Skipping Isoform:
ENSP00000296092





     
      









    
Other Inclusion Isoforms:
ENSP00000404336, ENSP00000404354
          









    
Other Skipping Isoforms:
ENSP00000391573, ENSP00000401311
  



Associated events






Other assemblies


hg38




Conservation


Mouse
(mm10)
chr9:122926310-122926454 
HIGH PSI
MmuEX6070030
(Zfp105)
Mouse
(mm9)
chr9:122835428-122835572 
HIGH PSI
MmuEX6070030
(Zfp105)
Rat
(rn6)
chr8:132004677-132004821 
HIGH PSI
RnoEX0101015
(Zfp105)
Cow
(bosTau6)
chr22:16497843-16497987 
HIGH PSI
BtaEX0041261
(ZNF35)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TTGAGAGAAGCCATGGCCCTA

				
R: 
GGGGTTTTTCAGCTTCCTCACA

				
Band lengths: 
249-394

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • The Cancer Genome Atlas (TCGA)
  • Genotype-Tissue Expression Project (GTEx)
  • Autistic and control brains
  • Pre-implantation embryo development






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"