HsaEX0073627 @ hg19

Exon Skipping

Gene

ENSG00000197050 | ZNF420

Description

zinc finger protein 420 [Source:HGNC Symbol;Acc:20649]

Coordinates

chr19:37581897-37618344:+

Coord C1 exon

chr19:37581897-37582023

Coord A exon

chr19:37586933-37587017

Coord C2 exon

chr19:37618030-37618344

Length

85 bp

Sequences

Splice sites

3' ss Seq

GACAATTATTTTTTTCTCAGCAC

3' ss Score

5.46

5' ss Seq

TTTGTAAGT

5' ss Score

7.4

Exon sequences

Seq C1 exon

AAATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAGAGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATGTGATGTTGGAGAACTATAGCAACTTGGTATCACTAG

Seq A exon

CACTCTGAAGATATTATTCCACTGTCCTCTGGCTTCTATTGTTGCTCTTGAGAAGTCTGCCATCTGTTTCATTGTTATTCCTTTT

Seq C2 exon

ACTTGCCTTCAAGGTGTGCAAGTAAGGACTTATCTCCAGAAAAGAACACTTATGAAACAGAATTATCCCAATGGGAAATGAGTGACAGACTTGAAAACTGTGATCTTGAAGAGTCCAATTCCAGGGATTATTTGGAAGCCAAAGGCAAGATGGAGAAGCAACAAGAAAATCAGAAGGAATATTTCAGGCAAGGGATGATCATATATGACAAAATGTCCATTTTCAACCAGCATACTTACTTATCTCAACATTCAAGATGTCATTCTACTGAGAAACCCTATAAATGTAAGGAATGTGGGAAAGCCTTCAGACGAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000197050-'3-6,'3-4,4-6

Average complexity

C1

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence inclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.000 A=0.000 C2=0.084

Domain overlap (PFAM):

C1:

PF0135222=KRAB=WD(100=95.3)

A:

PF0135222=KRAB=PD(0.1=0.0)

C2:

PF0135222=KRAB=PD(0.1=0.0),PF134651=zf-H2C2_2=WD(100=4.0),PF079757=C1_4=WD(100=8.2),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=3.9),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=3.9),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.0),PF097235=Zn-ribbon_8=WD(100=6.7),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=3.9),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.0)

Main Inclusion Isoform:

ENSP00000467369

Main Skipping Isoform:

ENSP00000338770

Other Inclusion Isoforms:

NA

Other Skipping Isoforms:

ENSP00000306102, ENSP00000466057, ENSP00000467772

Associated events

Other assemblies

hg38

Conservation

Mouse

(mm10)

No conservation detected

Mouse

(mm9)

No conservation detected

Rat

(rn6)

No conservation detected

Cow

(bosTau6)

chr18:47706935-47707019

ALTERNATIVE

BtaEX0041305

(ZNF420)

Chicken

(galGal4)

No conservation detected

Chicken

(galGal3)

No conservation detected

Zebrafish

(danRer10)

No conservation detected

Fruitfly

(dm6)

No conservation detected

Primers PCR

Suggestions for RT-PCR validation

F:

AAGAGTGGGAATGCCTGGACT

R:

TCTGTCACTCATTTCCCATTGGG

Band lengths:

173-258

Functional annotations

(Submit an annotation)

There are 0 annotated functions for this event

GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]

SPECIAL DATASETS

The Cancer Genome Atlas (TCGA)
Genotype-Tissue Expression Project (GTEx)
Autistic and control brains
Pre-implantation embryo development

Other AS DBs:

FasterDB (Includes CLIP-seq data)

AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)

APPRIS (Selection of principal isoform)

DEU primates (Only for human)

Special

HsaEX0073627 @ hg19

GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]

SPECIAL DATASETS