HsaEX0074293 @ hg19
Exon Skipping
Gene
ENSG00000181220 | ZNF746
Description
zinc finger protein 746 [Source:HGNC Symbol;Acc:21948]
Coordinates
chr7:149189950-149191594:-
Coord C1 exon
chr7:149191295-149191594
Coord A exon
chr7:149191080-149191161
Coord C2 exon
chr7:149189950-149190063
Length
82 bp
Sequences
Splice sites
3' ss Seq
CCGTGTATTTCTCCGAGCAGGAG
3' ss Score
6.12
5' ss Seq
TGGGTAAGG
5' ss Score
9.08
Exon sequences
Seq C1 exon
ATTTCTCCGTGGACGATGGCAGCCACGATTCAGGCCATGGAGAGGAAGATTGAATCGCAGGCTGCTCGCCTGCTTTCCCTAGAAGGTCGAACCGGGATGGCCGAGAAGAAGCTGGCTGATTGCGAGAAGACAGCCGTGGAGTTCGGGAACCAGCTGGAGGGCAAGTGGGCCGTGCTGGGGACCCTGCTGCAGGAGTACGGGCTGCTGCAGAGGCGGCTGGAGAACGTGGAGAACCTGCTGCGCAACAGGAACTTCTGGATCCTGCGGCTGCCCCCGGGCAGCAAGGGGGAGTCCCCTAAG
Seq A exon
GAGTGGGGCAAGCTGGAGGACTGGCAGAAGGAGCTCTACAAGCACGTGATGAGGGGCAACTACGAGACGCTGGTCTCCCTGG
Seq C2 exon
ACTACGCCATCTCCAAGCCCGAGGTCCTCTCCCAGATTGAACAAGGGAAGGAGCCCTGCAACTGGCGCCGCCCTGGCCCCAAGATTCCAGATGTTCCTGTGGACCCCAGTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000181220-'1-4,'1-2,2-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.039 A=0.071 C2=0.615
Domain overlap (PFAM):
C1:
PF124173=DUF3669=WD(100=74.0),PF0135222=KRAB=PU(6.5=2.0)
A:
PF0135222=KRAB=FE(87.1=100)
C2:
PF0135222=KRAB=PD(0.1=0.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGAACGTGGAGAACCTGCTG
R:
CATCTGGAATCTTGGGGCCAG
Band lengths:
174-256
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)