HsaEX1010645 @ hg38
Exon Skipping
Gene
ENSG00000168928 | CTRB2
Description
chymotrypsinogen B2 [Source:HGNC Symbol;Acc:HGNC:2522]
Coordinates
chr16:75204096-75205513:-
Coord C1 exon
chr16:75205333-75205513
Coord A exon
chr16:75204773-75204906
Coord C2 exon
chr16:75204096-75204322
Length
134 bp
Sequences
Splice sites
3' ss Seq
ACCCTCCTCCTGTCCTGCAGCCA
3' ss Score
9.84
5' ss Seq
ATGGTGAGG
5' ss Score
7.61
Exon sequences
Seq C1 exon
GTCTTCAAGAACCCCAAGTTCAGCATTCTGACCGTGAACAATGACATCACCCTGCTGAAGCTGGCCACACCTGCCCGCTTCTCCCAGACAGTGTCCGCCGTGTGCCTGCCCAGCGCCGACGACGACTTCCCCGCGGGGACACTGTGTGCCACCACAGGCTGGGGCAAGACCAAGTACAACG
Seq A exon
CCAACAAGACCCCTGACAAGCTGCAGCAGGCAGCCCTGCCCCTCCTGTCCAATGCCGAATGCAAGAAGTCCTGGGGCAGGAGGATCACCGACGTGATGATCTGTGCCGGGGCCAGTGGCGTCTCCTCCTGCATG
Seq C2 exon
GGTGACTCTGGAGGCCCCCTGGTCTGCCAGAAGGACGGAGCCTGGACCCTGGTGGGCATTGTGTCCTGGGGCAGCCGCACCTGCTCTACCACCACGCCCGCTGTGTACGCCCGTGTCGCCAAGCTCATACCCTGGGTGCAGAAGATCCTGGCCGCCAACTGAGCCCGCAGCTCCTGCCACCCCTGCCTTAAGATTTCCCATTAAATGCATCTGTTTAGAAGCCCTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168928_CASSETTE1
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.008 A=0.004 C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(26.9=100)
A:
PF0008921=Trypsin=FE(22.6=100)
C2:
PF0008921=Trypsin=PD(20.2=83.3)
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGCTTCTCCCAGACAGTGTC
R:
GGATCTTCTGCACCCAGGGTA
Band lengths:
254-388
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains