HsaEX1023284 @ hg38
Exon Skipping
Gene
ENSG00000175221 | MED16
Description
mediator complex subunit 16 [Source:HGNC Symbol;Acc:HGNC:17556]
Coordinates
chr19:871926-875454:-
Coord C1 exon
chr19:875244-875454
Coord A exon
chr19:873449-873582
Coord C2 exon
chr19:871926-872118
Length
134 bp
Sequences
Splice sites
3' ss Seq
CGACCCACGTCTCCTTGTAGACA
3' ss Score
7
5' ss Seq
CAGGTGCGC
5' ss Score
9.1
Exon sequences
Seq C1 exon
GTCCTCTCCACCCGGATCCTGGCCATGAAGGCCTCGCTCTGCAAGCTGTCGCCCTGCACGGTGACCCGCGTGTGCGACTACCACACCAAGCTCTTCCTCATCGCCATCAGCTCCACCCTGAAGTCGCTGCTGCGCCCCCACTTTCTCAACACGCCTGACAAGAGCCCCGGCGACCGGCTGACCGAGATCTGCACCAAGATCACCGACGTCG
Seq A exon
ACATTGACAAGGTCATGATCAACCTCAAGACGGAGGAATTTGTGCTGGACATGAACACACTGCAGGCGCTGCAGCAGCTCTTGCAGTGGGTGGGCGACTTCGTGCTGTACCTGCTGGCCAGCCTACCCAACCAG
Seq C2 exon
GGTTCCCTGCTGAGGCCGGGCCACAGCTTTCTGCGGGACGGCACCTCGCTGGGCATGCTTCGGGAATTGATGGTGGTCATCCGCATCTGGGGCCTTCTGAAGCCCAGCTGCCTGCCCGTGTATACGGCCACCTCGGATACCCAGGACAGCATGTCCCTGCTCTTCCGCCTGCTCACCAAGCTCTGGATCTGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175221_MULTIEX1-11/15=10-13
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.014 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF116353=Med16=PD(0.9=4.2),PF116353=Med16=FE(78.7=100)
A:
PF116353=Med16=FE(10.8=100)
C2:
PF116353=Med16=FE(8.7=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATCAGCTCCACCCTGAAGTC
R:
GGTATCCGAGGTGGCCGTATA
Band lengths:
248-382
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains