HsaEX6000986 @ hg19
Exon Skipping
Gene
ENSG00000011405 | PIK3C2A
Description
phosphoinositide-3-kinase, class 2, alpha polypeptide [Source:HGNC Symbol;Acc:8971]
Coordinates
chr11:17167215-17169175:-
Coord C1 exon
chr11:17169064-17169175
Coord A exon
chr11:17167410-17167489
Coord C2 exon
chr11:17167215-17167278
Length
80 bp
Sequences
Splice sites
3' ss Seq
GTGTATATGTGTTTGTTTAGGCA
3' ss Score
7.68
5' ss Seq
GAGGTATAT
5' ss Score
7.3
Exon sequences
Seq C1 exon
TAATCATTGCCTTGGAAGTCATGAGCATATTCAAAACTGTCGAAAATGGGACACAGAAATTAGACTACAACTCTTGACCTTCAGTGCAATGTGTCAAAATCTGGCCCGAACA
Seq A exon
GCAGAAGATGATGAAACACCCGTGGATTTAAACAAACACCTGTATCAAATAGAAAAACCTTGCAAAGAAGCCATGACGAG
Seq C2 exon
ACACCCTGTTGAAGAACTCTTAGATTCTTATCACAACCAAGTAGAACTGGCTCTTCAAATTGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000011405-'4-6,'4-5,5-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.037 C2=0.045
Domain overlap (PFAM):
C1:
PF0079413=PI3K_rbd=PD(27.9=76.3)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATTGCCTTGGAAGTCATGAGC
R:
TTTGAAGAGCCAGTTCTACTTGGT
Band lengths:
167-247
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)