HsaEX6001100 @ hg38
Exon Skipping
Gene
ENSG00000188162 | OTOG
Description
otogelin [Source:HGNC Symbol;Acc:HGNC:8516]
Coordinates
chr11:17557118-17569288:+
Coord C1 exon
chr11:17557118-17557323
Coord A exon
chr11:17558185-17558315
Coord C2 exon
chr11:17569156-17569288
Length
131 bp
Sequences
Splice sites
3' ss Seq
ATGTCAGCTCCCTCCTCCAGGGA
3' ss Score
8.23
5' ss Seq
CAGGTCTGG
5' ss Score
5.06
Exon sequences
Seq C1 exon
GGTCCAACTGCCACATGTCATGGGGAGCGCGCGTCTGCAGCAGCTTGCCGGCTATGTCATCGTGCGGCATCAGTCAGCCTTCACACTGGCCTGGGATGGTGCCTCGGCTGTCTACATCAAGATGAGTCCAGAGCTTCTGGGCTGGACCCATGGGCTGTGTGGGAACAACAATGCTGACCCCAAGGATGATCTGGTGACCAGCTCTG
Seq A exon
GGAAGCTGACTGACGACGTGGTTGAGTTTGTGCACAGCTGGCAGGAGCAGGCCCCTAACCAGCCTCCAGGGCCCACAACTTCCTCCCTGCCTCGCCCACCGTGCCTACAGCAGAACCCAGGAACCATGCAG
Seq C2 exon
AACCAAGATGGAGCCTGTGTCCAGTCAGTGTCAGTGATTCTGCACCAGGACCCTCGGAGGCAGGTGACCCTGACCCAGGCAGGGGATGTCCTTCTGTTTGACCAGTACAAGATCATCCCGCCATACACAGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188162_MULTIEX1-3/9=2-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.100 A=0.523 C2=0.000
Domain overlap (PFAM):
C1:
PF0009420=VWD=FE(45.7=100)
A:
PF0009420=VWD=PD(0.7=2.3),PF087426=C8=PU(1.3=2.3)
C2:
PF0009420=VWD=FE(28.2=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TATGTCATCGTGCGGCATCAG
R:
AAACAGAAGGACATCCCCTGC
Band lengths:
253-384
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains