HsaEX6002234 @ hg19
Exon Skipping
Gene
ENSG00000167987 | VPS37C
Description
vacuolar protein sorting 37 homolog C (S. cerevisiae) [Source:HGNC Symbol;Acc:26097]
Coordinates
chr11:60900727-60906307:-
Coord C1 exon
chr11:60906209-60906307
Coord A exon
chr11:60901508-60901679
Coord C2 exon
chr11:60900727-60900809
Length
172 bp
Sequences
Splice sites
3' ss Seq
CTGTTGTCCTGCCCTTTTAGGTC
3' ss Score
12.74
5' ss Seq
TGGGTAGGG
5' ss Score
4.66
Exon sequences
Seq C1 exon
GGAAGGATGGAGACGCTGAAGGATAAGACCCTGCAGGAGCTGGAGGAGTTGCAGAATGACTCGGAGGCGATTGACCAGCTGGCCCTGGAGTCCCCTGAG
Seq A exon
GTCCAGGACCTACAGCTGGAACGGGAGATGGCACTGGCCACCAACCGGAGCCTGGCAGAGCGGAACTTGGAGTTCCAGGGTCCCCTGGAGATCAGCCGCTCAAACCTCTCGGATAGATACCAGGAGCTCCGGAAGCTCGTGGAGCGGTGCCAGGAGCAGAAGGCAAAGCTGG
Seq C2 exon
AGAAATTTTCTTCAGCACTGCAGCCAGGGACCTTGTTAGACCTTCTGCAGGTGGAAGGCATGAAGATCGAAGAAGAGTCCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167987-'2-3,'2-2,4-3=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.855 A=0.121 C2=0.250
Domain overlap (PFAM):
C1:
PF072008=Mod_r=PU(18.6=87.1),PF056227=HOOK=PU(31.2=96.8)
A:
PF072008=Mod_r=FE(39.3=100),PF056227=HOOK=FE(59.4=100),PF0001021=HLH=PU(83.3=43.1)
C2:
PF072008=Mod_r=FE(18.6=100),PF056227=HOOK=PD(7.3=25.0),PF0001021=HLH=PD(13.3=14.3)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGGATGGAGACGCTGAAGGA
R:
TCGGACTCTTCTTCGATCTTCA
Band lengths:
179-351
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)