HsaEX6003452 @ hg38
Exon Skipping
Gene
ENSG00000162337 | LRP5
Description
LDL receptor related protein 5 [Source:HGNC Symbol;Acc:HGNC:6697]
Coordinates
chr11:68425102-68429700:+
Coord C1 exon
chr11:68425102-68425292
Coord A exon
chr11:68425978-68426187
Coord C2 exon
chr11:68429575-68429700
Length
210 bp
Sequences
Splice sites
3' ss Seq
GGCCCACGGGCTGCTTGCAGGGG
3' ss Score
4.94
5' ss Seq
TCTGTACGT
5' ss Score
4.47
Exon sequences
Seq C1 exon
GTACCTGTACTTCACCAACATGCAGGACCGGGCAGCCAAGATCGAACGCGCAGCCCTGGACGGCACCGAGCGCGAGGTCCTCTTCACCACCGGCCTCATCCGCCCTGTGGCCCTGGTGGTGGACAACACACTGGGCAAGCTGTTCTGGGTGGACGCGGACCTGAAGCGCATTGAGAGCTGTGACCTGTCAG
Seq A exon
GGGCCAACCGCCTGACCCTGGAGGACGCCAACATCGTGCAGCCTCTGGGCCTGACCATCCTTGGCAAGCATCTCTACTGGATCGACCGCCAGCAGCAGATGATCGAGCGTGTGGAGAAGACCACCGGGGACAAGCGGACTCGCATCCAGGGCCGTGTCGCCCACCTCACTGGCATCCATGCAGTGGAGGAAGTCAGCCTGGAGGAGTTCT
Seq C2 exon
CAGCCCACCCATGTGCCCGTGACAATGGTGGCTGCTCCCACATCTGTATTGCCAAGGGTGATGGGACACCACGGTGCTCATGCCCAGTCCACCTCGTGCTCCTGCAGAACCTGCTGACCTGTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162337-'55-45,'55-44,56-45
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.116 A=0.070 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=66.2),PF0005812=Ldl_recept_b=PU(48.7=29.2)
A:
PF0005812=Ldl_recept_b=PD(48.7=26.8)
C2:
PF146701=FXa_inhibition=WD(100=86.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTCACCAACATGCAGGACC
R:
TCCACAGGTCAGCAGGTTCTG
Band lengths:
308-518
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains