HsaEX6003911 @ hg38
Exon Skipping
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77162853-77172885:+
Coord C1 exon
chr11:77162853-77162988
Coord A exon
chr11:77166056-77166162
Coord C2 exon
chr11:77172748-77172885
Length
107 bp
Sequences
Splice sites
3' ss Seq
CTGCTGTTTGCTGCTTGCAGGCT
3' ss Score
8.26
5' ss Seq
ATGGTAAGC
5' ss Score
9.26
Exon sequences
Seq C1 exon
GGCACAGACACCACCATGTTACACAAGCTGAACTCCCAGCACAAGCTCAACGCCAACTACATCCCCCCCAAGAACAACCATGAGACCCAGTTTGGCATCAACCATTTTGCAGGCATCGTCTACTATGAGACCCAAG
Seq A exon
GCTTCCTGGAGAAGAACCGAGACACCCTGCATGGGGACATTATCCAGCTGGTCCACTCCTCCAGGAACAAGTTCATCAAGCAGATCTTCCAGGCCGATGTCGCCATG
Seq C2 exon
GGCGCCGAGACCAGGAAGCGCTCGCCCACACTTAGCAGCCAGTTCAAGCGGTCACTGGAGCTGCTGATGCGCACGCTGGGTGCCTGCCAGCCCTTCTTTGTGCGATGCATCAAGCCCAATGAGTTCAAGAAGCCCATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474-'29-31,'29-23,30-31=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.196 A=0.000 C2=0.012
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(6.8=100)
A:
PF0006316=Myosin_head=FE(5.3=100)
C2:
PF0006316=Myosin_head=FE(6.8=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCACAGACACCACCATGTTA
R:
GGCTTGATGCATCGCACAAAG
Band lengths:
252-359
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains