HsaEX6004944 @ hg38
Exon Skipping
Gene
ENSG00000137648 | TMPRSS4
Description
transmembrane protease, serine 4 [Source:HGNC Symbol;Acc:HGNC:11878]
Coordinates
chr11:118111741-118114927:+
Coord C1 exon
chr11:118111741-118111900
Coord A exon
chr11:118113269-118113435
Coord C2 exon
chr11:118114829-118114927
Length
167 bp
Sequences
Splice sites
3' ss Seq
CCAGCTGTCTCTACCCCCAGGAA
3' ss Score
10.31
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
Exon sequences
Seq C1 exon
CCTGTGGGAAGAGCCTGAAGACCCCCCGTGTGGTGGGTGTGGAGGAGGCCTCTGTGGATTCTTGGCCTTGGCAGGTCAGCATCCAGTACGACAAACAGCACGTCTGTGGAGGGAGCATCCTGGACCCCCACTGGGTCCTCACGGCAGCCCACTGCTTCAG
Seq A exon
GAAACATACCGATGTGTTCAACTGGAAGGTGCGGGCAGGCTCAGACAAACTGGGCAGCTTCCCATCCCTGGCTGTGGCCAAGATCATCATCATTGAATTCAACCCCATGTACCCCAAAGACAATGACATCGCCCTCATGAAGCTGCAGTTCCCACTCACTTTCTCAG
Seq C2 exon
GCACAGTCAGGCCCATCTGTCTGCCCTTCTTTGATGAGGAGCTCACTCCAGCCACCCCACTCTGGATCATTGGATGGGGCTTTACGAAGCAGAATGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137648-'19-22,'19-17,20-22
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF154941=SRCR_2=PD(5.4=9.3),PF0008921=Trypsin=PU(19.1=79.6)
A:
PF0008921=Trypsin=FE(24.9=100)
C2:
PF0008921=Trypsin=PD(24.2=94.1)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGTGGGAAGAGCCTGAAGA
R:
AAGCCCCATCCAATGATCCAG
Band lengths:
242-409
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains