HsaEX6007398 @ hg38
Exon Skipping
Gene
ENSG00000105877 | DNAH11
Description
dynein axonemal heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:2942]
Coordinates
chr7:21725811-21738866:+
Coord C1 exon
chr7:21725811-21725984
Coord A exon
chr7:21735640-21735844
Coord C2 exon
chr7:21738701-21738866
Length
205 bp
Sequences
Splice sites
3' ss Seq
CATTCTGTTTCTCCTCCCAGACA
3' ss Score
10.23
5' ss Seq
AAAGTAAGT
5' ss Score
9.72
Exon sequences
Seq C1 exon
ATTTCTGATTATCAAGCTGACTTCAGTCGGTGGTGGCAGAAAGAGATGAAAGCAGTGAAATTTCCGTCGCAGGGAACAATCTTTGATTATTATGTGGACCACAAAACTAAGAAATTATTGCCCTGGGCTGACAAAATTGCCCAGTTTACTATGGATCCAGATGTGCCTCTGCAG
Seq A exon
ACAGTTCTCGTTCACACAACAGAGACAGCTCGTCTTAGATATTTCATGGAGTTGTTGCTTGAGAAAGGAAAACCTCTAATGCTAGTAGGAAATGCAGGAGTGGGAAAAACAGTCTTTGTAGGTGACACATTGGCAAGTCTCTCTGAGGATTACATAGTATCCCGTGTGCCTTTCAACTACTACACGACATCCACAGCTCTGCAAA
Seq C2 exon
AAATTCTTGAGAAACCCCTAGAGAAAAAAGCTGGTCATAACTATGGTCCTGGAGGAAATAAAAAATTGATTTATTTTATCGACGACATGAACATGCCTGAAGTGGACTTATATGGCACCGTTCAGCCTCACACCCTGATCCGGCAGCATATTGATTATGGACATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105877-'72-75,'72-72,73-75
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF127752=AAA_7=PU(3.3=15.5)
A:
PF127752=AAA_7=PU(40.0=98.6)
C2:
PF127752=AAA_7=FE(20.3=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGTGGTGGCAGAAAGAGATG
R:
CAATATGCTGCCGGATCAGGG
Band lengths:
300-505
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains