HsaEX6015720 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:141247226-141480533:-
Coord C1 exon
chr2:141480396-141480533
Coord A exon
chr2:141254522-141254641
Coord C2 exon
chr2:141247226-141247354
Length
120 bp
Sequences
Splice sites
3' ss Seq
TATTTGTTTTTTCTCTACAGAAC
3' ss Score
10.76
5' ss Seq
AAGGTAAGT
5' ss Score
11
Exon sequences
Seq C1 exon
GTCCCGAGGAGGTAGAAATCAAGTGCCCCTTGAATCACATTGCTTGCCTTGGTACCAACAAATGTGTTCATTTATCCCAGCTGTGCAATGGTGTCTTGGACTGCCCAGATGGGTATGACGAAGGAGTACATTGTCAGG
Seq A exon
AACTGTTATCCAATTGCCAACAGCTGAATTGTCAGTATAAATGTACAATGGTCAGAAATAGTACAAGATGTTACTGTGAGGATGGATTCGAAATAACAGAAGATGGGAGAAGCTGTAAAG
Seq C2 exon
ATCAAGATGAATGTGCTGTTTATGGTACATGCAGCCAGACCTGCAGAAACACACATGGATCCTACACTTGCAGTTGTGTGGAAGGCTACCTAATGCAGCCAGACAACAGATCTTGCAAGGCTAAAATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'9-28,'9-27,12-28
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=PD(0.1=0.0),PF0005713=Ldl_recept_a=WD(100=83.0)
A:
PF126622=cEGF=PU(83.3=48.8)
C2:
PF126622=cEGF=PD(12.5=6.8),PF146701=FXa_inhibition=WD(100=79.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAGGTAGAAATCAAGTGCCCC
R:
AAGATCTGTTGTCTGGCTGCA
Band lengths:
245-365
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains