HsaEX6015737 @ hg19
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
low density lipoprotein receptor-related protein 1B [Source:HGNC Symbol;Acc:6693]
Coordinates
chr2:141607671-141625403:-
Coord C1 exon
chr2:141625159-141625403
Coord A exon
chr2:141609221-141609352
Coord C2 exon
chr2:141607671-141607898
Length
132 bp
Sequences
Splice sites
3' ss Seq
ATTTCACTGTGTAATTACAGCTC
3' ss Score
5.82
5' ss Seq
ATGGTAAAT
5' ss Score
6.41
Exon sequences
Seq C1 exon
GTCAGATGCTATTTATTCAGCCCTCTATGATGGAACAAACATGATAGAAATCATCCGAGGTCATGAATACCTTTCCCATCCCTTTGCTGTGTCTCTATATGGGAGTGAAGTCTACTGGACAGACTGGAGGACCAACACATTGTCCAAAGCCAATAAGTGGACAGGGCAGAATGTCAGTGTGATTCAGAAAACCAGTGCACAGCCATTTGACCTTCAGATATACCATCCCAGTCGCCAGCCACAGG
Seq A exon
CTCCCAATCCTTGTGCAGCTAATGATGGCAAAGGCCCCTGCTCTCACATGTGTCTAATCAATCACAATAGGAGTGCTGCCTGTGCGTGCCCCCACTTGATGAAGCTTTCTTCAGACAAGAAGACCTGCTATG
Seq C2 exon
AAATGAAAAAATTTCTTCTTTATGCAAGACGTTCTGAAATCAGAGGAGTGGATATTGACAATCCATACTTTAACTTCATCACGGCATTTACAGTCCCTGATATTGATGACGTTACTGTGATAGACTTCGATGCATCTGAGGAACGTTTATACTGGACAGATATTAAAACACAAACCATTAAACGAGCTTTTATTAACGGAACTGGGTTAGAAACTGTTATTTCAAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'27-28,'27-27,28-28=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.024 A=0.156 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF146701=FXa_inhibition=WD(100=86.7)
C2:
PF0005812=Ldl_recept_b=PU(70.7=37.7)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TATACCATCCCAGTCGCCAGC
R:
ACAGTTTCTAACCCAGTTCCGT
Band lengths:
244-376
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)