HsaEX6015748 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:140700250-140702292:-
Coord C1 exon
chr2:140702141-140702292
Coord A exon
chr2:140701721-140701845
Coord C2 exon
chr2:140700250-140700621
Length
125 bp
Sequences
Splice sites
3' ss Seq
TATGTTCAACTTTTTGGCAGAGC
3' ss Score
6.18
5' ss Seq
AAGGTCAGC
5' ss Score
7.09
Exon sequences
Seq C1 exon
GAAAATAAATTGTACTGGTGTGATGCTCGCACAGACAAGATAGAGAGAATCGACCTTGAGACTGGAGGGAATCGCGAGATGGTGCTGTCAGGAAGCAATGTGGATATGTTTTCAGTTGCAGTCTTTGGGGCTTACATCTACTGGTCTGACAG
Seq A exon
AGCACATGCAAACGGGTCTGTCAGAAGGGGCCACAAGAATGATGCCACAGAAACGATAACCATGAGAACCGGCCTTGGAGTCAACCTGAAGGAGGTTAAAATATTTAACCGAGTAAGAGAGAAAG
Seq C2 exon
GGACCAATGTTTGTGCCAGGGACAATGGTGGCTGTAAGCAACTCTGTCTTTATCGAGGAAATTCCCGGAGAACTTGTGCTTGTGCCCATGGATATTTGGCAGAAGATGGAGTTACTTGCCTGAGGCATGAAGGCTATTTACTGTATTCAGGAAGAACAATATTAAAAAGTATACATCTTTCTGATGAAACCAATTTAAATTCCCCAATAAGGCCATATGAGAATCCACGTTATTTCAAGAATGTCATAGCCTTGGCTTTTGACTATAATCAAAGAAGAAAAGGTACCAACCGAATCTTTTACAGTGATGCACACTTTGGAAATATACAGCTTATTAAAGACAACTGGGAAGACAGACAAGTAATTGTTGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'66-94,'66-93,67-94
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.163 C2=0.016
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=78.4)
A:
NO
C2:
PF146701=FXa_inhibition=WD(100=28.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGTACTGGTGTGATGCTCGC
R:
TGCCAAATATCCATGGGCACA
Band lengths:
244-369
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains