MmuEX1016402 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:41110754-41112835:-
Coord C1 exon
chr2:41112684-41112835
Coord A exon
chr2:41112259-41112383
Coord C2 exon
chr2:41110754-41111125
Length
125 bp
Sequences
Splice sites
3' ss Seq
TATCTTCGACTTTTTGGCAGAGC
3' ss Score
5.43
5' ss Seq
AAGGTCAGC
5' ss Score
7.09
Exon sequences
Seq C1 exon
GAAAATAAATTATACTGGTGTGATGCTCGCTCAGACAAGATAGAGAGAATTGACCTTGACACTGGTGCGAATCGTGAAGTGTTGCTGTCTGGGAGCAACGTGGATCTGTTTTCAGTTGCAGTCTTTGGGGCTTACATCTACTGGTCTGACAG
Seq A exon
AGCACACGCCAATGGATCAGTCAGAAGAGGCCACAAGAATGATGCCACAGAGACAGTAACCATGAGAACAGGACTTGGAGTTAACCTAAAGGAGATCAAAATTTTTAACCGAGTAAGAGAGAAAG
Seq C2 exon
GGACCAATGTCTGTGCCAAAGAAAATGGTGGCTGTCAGCAACTATGTCTTTATCGAGGAAATTCCCGAAGAACCTGTGCCTGTGCCCATGGATATTTGGCTGGGGATGGAGTTACTTGTCTAAGGCATGAAGGTTATTTGCTATATTCAGGAAGAACAATATTAAAAAGCATACATCTTTCTGATGAAACCAATTTAAATTCCCCAGTACGGCCCTACGAGAACCCAAATTATTTCAAGAATATTATAGCCCTGGCTTTTGACTATAATCAAAGAAGAGAAGGTACCAATCGGATCTTTTACAGTGATGCACACTTTGGAAATATACAGCTTATTAAAGATAACTGGGAAGACAGACAAGTAATTGTGGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'64-61,'64-60,65-61
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.209 C2=0.024
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=80.4)
A:
NO
C2:
PF146701=FXa_inhibition=WD(100=28.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGTGATGCTCGCTCAGACAA
R:
AGTAACTCCATCCCCAGCCAA
Band lengths:
251-376
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types