HsaEX6016296 @ hg19
Exon Skipping
Gene
ENSG00000115271 | GCA
Description
grancalcin, EF-hand calcium binding protein [Source:HGNC Symbol;Acc:15990]
Coordinates
chr2:163212948-163215667:+
Coord C1 exon
chr2:163212948-163212991
Coord A exon
chr2:163213268-163213415
Coord C2 exon
chr2:163215554-163215667
Length
148 bp
Sequences
Splice sites
3' ss Seq
TTTGTTAATAAAACTATCAGAGA
3' ss Score
0.87
5' ss Seq
TGGGTAAGA
5' ss Score
8.91
Exon sequences
Seq C1 exon
CCTTCAGTTTGGAAACCTGCAGAATTATGATTGCCATGTTGGAT
Seq A exon
AGAGATCACACAGGAAAAATGGGATTTAATGCATTCAAAGAGCTATGGGCAGCTCTTAATGCCTGGAAGGAAAACTTCATGACTGTTGATCAAGATGGAAGTGGCACAGTAGAACATCATGAGTTGCGTCAAGCCATTGGTCTTATGG
Seq C2 exon
GTTATAGGTTGAGTCCTCAAACATTAACTACTATTGTTAAACGTTATAGCAAGAATGGCAGAATTTTCTTTGATGATTATGTTGCTTGCTGTGTGAAGCTTCGAGCATTGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115271-'11-14,'11-13,15-14=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.008 C2=0.000
Domain overlap (PFAM):
C1:
PF111973=DUF2835=PD(10.5=40.0),PF138331=EF-hand_8=FE(32.6=100)
A:
PF138331=EF-hand_8=PD(31.0=36.0),PF134991=EF-hand_7=PU(48.3=58.0)
C2:
PF134991=EF-hand_7=PD(50.0=76.9)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTTCAGTTTGGAAACCTGCA
R:
TCAATGCTCGAAGCTTCACACA
Band lengths:
155-303
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)