HsaEX6016555 @ hg19
Exon Skipping
Gene
ENSG00000081479 | LRP2
Description
low density lipoprotein receptor-related protein 2 [Source:HGNC Symbol;Acc:6694]
Coordinates
chr2:170060492-170062698:-
Coord C1 exon
chr2:170062533-170062698
Coord A exon
chr2:170061989-170062147
Coord C2 exon
chr2:170060492-170060781
Length
159 bp
Sequences
Splice sites
3' ss Seq
GACTCCTTTTGTATGACTAGGTA
3' ss Score
6.41
5' ss Seq
TCTGTAGGT
5' ss Score
2.49
Exon sequences
Seq C1 exon
GTATAGGGACTGCTGATGGCATTGCCTTTGACTGGATTACTAGAAGAATTTATTACAGTGACTACCTCAACCAGATGATTAATTCCATGGCTGAAGATGGGTCTAACCGCACTGTGATAGCCCGCGTTCCAAAACCAAGAGCAATTGTGTTAGATCCCTGCCAAGG
Seq A exon
GTACCTGTACTGGGCTGACTGGGATACACATGCCAAAATCGAGAGAGCCACATTGGGAGGAAACTTCCGCGTACCCATTGTGAACAGCAGTCTGGTCATGCCCAGTGGGCTGACTCTGGACTATGAAGAGGACCTTCTCTACTGGGTGGATGCTAGTCT
Seq C2 exon
GCAGAGGATTGAACGCAGCACTCTGACGGGCGTGGATCGTGAAGTCATTGTCAATGCAGCCGTTCATGCTTTTGGCTTGACTCTCTATGGCCAGTATATTTACTGGACTGACTTGTACACACAAAGAATTTACCGAGCTAACAAATATGACGGGTCAGGTCAGATTGCAATGACCACAAATTTGCTCTCCCAGCCCAGGGGAATCAACACTGTTGTGAAGAACCAGAAACAACAGTGTAACAATCCTTGTGAACAGTTTAATGGGGGCTGCAGCCATATCTGTGCACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000081479-'41-41,'41-40,42-41=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
PF0005812=Ldl_recept_b=WD(100=77.8),PF0005812=Ldl_recept_b=PU(23.1=16.7)
C2:
PF0005812=Ldl_recept_b=PD(74.4=29.6),PF146701=FXa_inhibition=PU(36.8=14.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGGGTCTAACCGCACTGTG
R:
ATTGCAATCTGACCTGACCCG
Band lengths:
242-401
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)