HsaEX6021091 @ hg19
Exon Skipping
Gene
ENSG00000109063 | MYH3
Description
myosin, heavy chain 3, skeletal muscle, embryonic [Source:HGNC Symbol;Acc:7573]
Coordinates
chr17:10541360-10542506:-
Coord C1 exon
chr17:10542361-10542506
Coord A exon
chr17:10542190-10542280
Coord C2 exon
chr17:10541360-10541749
Length
91 bp
Sequences
Splice sites
3' ss Seq
TTCTACATTTCTCTTCACAGGAA
3' ss Score
10.84
5' ss Seq
CAGGTAGGA
5' ss Score
9.79
Exon sequences
Seq C1 exon
CTGGAAAGCTCCCTAGAACAAGAAAAGAAGCTCCGAGTAGACCTGGAAAGGAACAAAAGGAAATTGGAAGGAGACTTGAAGCTTGCTCAAGAGTCCATATTAGATCTGGAGAATGACAAGCAACAGCTGGACGAAAGGCTCAAGAA
Seq A exon
GAAAGATTTTGAATATTGTCAACTTCAAAGCAAAGTGGAAGATGAGCAGACACTGGGCCTCCAGTTTCAGAAGAAAATCAAAGAGTTGCAG
Seq C2 exon
GCTCGAATTGAGGAGCTGGAAGAGGAGATAGAGGCGGAGAGGGCCACCCGCGCGAAGACAGAGAAACAGCGCAGCGACTATGCCCGGGAGCTGGAGGAGCTGAGCGAGCGGCTGGAGGAGGCGGGAGGCGTCACCTCCACGCAGATAGAGCTCAACAAGAAGCGGGAGGCGGAGTTCCTGAAGCTGCGCAGGGACCTGGAGGAGGCCACACTGCAGCACGAAGCCATGGTGGCCGCGCTGAGGAAGAAGCATGCGGATAGTGTGGCCGAGCTTGGGGAGCAGATTGACAACCTGCAGCGGGTCAAGCAGAAGCTGGAGAAGGAGAAGAGCGAGTTCAAGCTGGAGATCGATGACCTCTCCAGCAGCATGGAGAGTGTGTCGAAATCTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063-'23-24,'23-23,24-24=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.020 A=0.000 C2=0.323
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=PD(1.0=4.1),PF0157614=Myosin_tail_1=PD(50.7=69.4),PF0157614=Myosin_tail_1=PU(1.6=28.6)
A:
PF0157614=Myosin_tail_1=FE(3.5=100)
C2:
PF0157614=Myosin_tail_1=FE(15.0=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGGACGAAAGGCTCAAGAA
R:
TGAGCTCTATCTGCGTGGAGG
Band lengths:
175-266
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)