HsaEX6021091 @ hg38
Exon Skipping
Gene
ENSG00000109063 | MYH3
Description
myosin heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:7573]
Coordinates
chr17:10638043-10639189:-
Coord C1 exon
chr17:10639044-10639189
Coord A exon
chr17:10638873-10638963
Coord C2 exon
chr17:10638043-10638432
Length
91 bp
Sequences
Splice sites
3' ss Seq
TTCTACATTTCTCTTCACAGGAA
3' ss Score
10.84
5' ss Seq
CAGGTAGGA
5' ss Score
9.79
Exon sequences
Seq C1 exon
CTGGAAAGCTCCCTAGAACAAGAAAAGAAGCTCCGAGTAGACCTGGAAAGGAACAAAAGGAAATTGGAAGGAGACTTGAAGCTTGCTCAAGAGTCCATATTAGATCTGGAGAATGACAAGCAACAGCTGGACGAAAGGCTCAAGAA
Seq A exon
GAAAGATTTTGAATATTGTCAACTTCAAAGCAAAGTGGAAGATGAGCAGACACTGGGCCTCCAGTTTCAGAAGAAAATCAAAGAGTTGCAG
Seq C2 exon
GCTCGAATTGAGGAGCTGGAAGAGGAGATAGAGGCGGAGAGGGCCACCCGCGCGAAGACAGAGAAACAGCGCAGCGACTATGCCCGGGAGCTGGAGGAGCTGAGCGAGCGGCTGGAGGAGGCGGGAGGCGTCACCTCCACGCAGATAGAGCTCAACAAGAAGCGGGAGGCGGAGTTCCTGAAGCTGCGCAGGGACCTGGAGGAGGCCACACTGCAGCACGAAGCCATGGTGGCCGCGCTGAGGAAGAAGCATGCGGATAGTGTGGCCGAGCTTGGGGAGCAGATTGACAACCTGCAGCGGGTCAAGCAGAAGCTGGAGAAGGAGAAGAGCGAGTTCAAGCTGGAGATCGATGACCTCTCCAGCAGCATGGAGAGTGTGTCGAAATCTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063-'31-27,'31-26,32-27=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.020 A=0.000 C2=0.323
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=PD(1.0=4.1),PF0157614=Myosin_tail_1=PD(50.7=69.4),PF0157614=Myosin_tail_1=PU(1.6=28.6)
A:
PF0003816=Filament=FE(10.9=100),PF0157614=Myosin_tail_1=FE(7.8=100)
C2:
PF0003816=Filament=FE(46.7=100),PF0157614=Myosin_tail_1=FE(33.3=100),PF131661=AAA_13=PU(19.1=37.7)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGGACGAAAGGCTCAAGAA
R:
TGAGCTCTATCTGCGTGGAGG
Band lengths:
175-266
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains