HsaEX6021525 @ hg38
Exon Skipping
Gene
ENSG00000034152 | MAP2K3
Description
mitogen-activated protein kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6843]
Coordinates
chr17:21312142-21315213:+
Coord C1 exon
chr17:21312142-21312281
Coord A exon
chr17:21313492-21313537
Coord C2 exon
chr17:21314147-21315213
Length
46 bp
Sequences
Splice sites
3' ss Seq
GCTGCACTATTCTCTCCTAGCCT
3' ss Score
4.62
5' ss Seq
ATGGTGAGT
5' ss Score
10.13
Exon sequences
Seq C1 exon
ATTGAGATGGCCATCCTGCGGTTCCCTTACGAGTCCTGGGGGACCCCGTTCCAGCAGCTGAAGCAGGTGGTGGAGGAGCCGTCCCCCCAGCTCCCAGCCGACCGTTTCTCCCCCGAGTTTGTGGACTTCACTGCTCAGTG
Seq A exon
CCTGAGGAAGAACCCCGCAGAGCGTATGAGCTACCTGGAGCTGATG
Seq C2 exon
GAGCACCCCTTCTTCACCTTGCACAAAACCAAGAAGACGGACATTGCTGCCTTCGTGAAGGAGATCCTGGGAGAAGACTCATAGGGGCTGGGCCTCGGACCCCACTCCGGCCCTCCAGAGCCCCACAGCCCCATCTGCGGGGGCAGTGCTCACCCACACCATAAGCTACTGCCATCCTGGCCCAGGGCATCTGGGAGGAACCGAGGGGGCTGCTCCCACCTGGCTCTGTGGCGAGCCATTTGTCCCAAGTGCCAAAGAAGCAGACCATTGGGGCTCCCAGCCAGGCCCTTGTCGGCCCCACCAGTGCCTCTCCCTGCTGCTCCTAGGACCCGTCTCCAGCTGCTGAGATCCTGGACTGAGGGGGCCTGGATGCCCCCTGTGGATGCTGCTGCCCCTGCACAGCAGGCTGCCAGTGCCTGGGTGGATGGGCCACCGCCTTGCCCAGCCTGGATGCCATCCAAGTTGTATATTTTTTTAATCTCTCGACTGAATGGACTTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000034152-'35-32,'35-30,37-32
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.074 A=0.014 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(17.6=100)
A:
PF0006920=Pkinase=FE(5.7=100)
C2:
PF0006920=Pkinase=PD(1.5=14.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTCCCTTACGAGTCCTGGGG
R:
CAAGGTGAAGAAGGGGTGCTC
Band lengths:
141-187
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains