HsaEX6021527 @ hg19
Exon Skipping
Gene
ENSG00000034152 | MAP2K3
Description
mitogen-activated protein kinase kinase 3 [Source:HGNC Symbol;Acc:6843]
Coordinates
chr17:21205455-21207865:+
Coord C1 exon
chr17:21205455-21205571
Coord A exon
chr17:21206495-21206546
Coord C2 exon
chr17:21207738-21207865
Length
52 bp
Sequences
Splice sites
3' ss Seq
CCTCCCCACCCCACCGCCAGATC
3' ss Score
8.36
5' ss Seq
GAGGTCAGT
5' ss Score
7.7
Exon sequences
Seq C1 exon
GGAGACGTGTGGATCTGCATGGAGCTCATGGACACATCCTTGGACAAGTTCTACCGGAAGGTGCTGGATAAAAACATGACAATTCCAGAGGACATCCTTGGGGAGATTGCTGTGTCT
Seq A exon
ATCGTGCGGGCCCTGGAGCATCTGCACAGCAAGCTGTCGGTGATCCACAGAG
Seq C2 exon
ATGTGAAGCCCTCCAATGTCCTTATCAACAAGGAGGGCCATGTGAAGATGTGTGACTTTGGCATCAGTGGCTACTTGGTGGACTCTGTGGCCAAGACGATGGATGCCGGCTGCAAGCCCTACATGGCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000034152-'15-13,'15-12,16-13=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(14.5=100)
A:
PF0006920=Pkinase=PD(12.7=88.9)
C2:
PF0006920=Pkinase=FE(16.0=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAGCTCATGGACACATCCT
R:
TTCACATGGCCCTCCTTGTTG
Band lengths:
144-196
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)