HsaEX6022307 @ hg19
Exon Skipping
Gene
ENSG00000002834 | LASP1
Description
LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:6513]
Coordinates
chr17:37026256-37046757:+
Coord C1 exon
chr17:37026256-37026511
Coord A exon
chr17:37034339-37034433
Coord C2 exon
chr17:37046673-37046757
Length
95 bp
Sequences
Splice sites
3' ss Seq
CCTCCTGTCTCCATCCCCAGTTC
3' ss Score
10.59
5' ss Seq
CGCGTGAGT
5' ss Score
8.4
Exon sequences
Seq C1 exon
AGTGCAGCCCCTCCTCCCCGCTGTGTTTATTAGGGGAAGGAGGGCGGAGGCGGAGGCCAGTTCCCCAGCTCCAGCCGCCGTCGCTGCTGCCTGTGTAGTTGCAGCCGCGGCCGCCTCCCGCCAGCTCGCCTCGGGGAACAGGACGCGCGTGAGCTCAGGCGTCCCCGCCCCAGCTTTTCTCGGAACCATGAACCCCAACTGCGCCCGGTGCGGCAAGATCGTGTATCCCACGGAGAAGGTGAACTGTCTGGATAAG
Seq A exon
TTCTGGCATAAAGCATGCTTCCATTGCGAGACCTGCAAGATGACACTGAACATGAAGAACTACAAGGGCTACGAGAAGAAGCCCTACTGCAACGC
Seq C2 exon
ACACTACCCCAAGCAGTCCTTCACCATGGTGGCGGACACCCCGGAAAACCTTCGCCTCAAGCAACAGAGTGAGCTCCAGAGTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000002834-'0-3,'0-1,2-3=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.155 C2=0.572
Domain overlap (PFAM):
C1:
PF062218=zf-C2HC5=PU(47.8=95.7),PF0041217=LIM=PU(31.6=78.3)
A:
PF062218=zf-C2HC5=PD(47.8=68.8),PF0041217=LIM=FE(54.4=100)
C2:
PF0041217=LIM=PD(10.5=20.7),PF0088013=Nebulin=PU(55.2=55.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCAGCTTTTCTCGGAACCAT
R:
TCTGGAGCTCACTCTGTTGCT
Band lengths:
168-263
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)