HsaEX6025982 @ hg19
Exon Skipping
Gene
ENSG00000186716 | BCR
Description
breakpoint cluster region [Source:HGNC Symbol;Acc:1014]
Coordinates
chr22:23613719-23615961:+
Coord C1 exon
chr22:23613719-23613779
Coord A exon
chr22:23615268-23615320
Coord C2 exon
chr22:23615821-23615961
Length
53 bp
Sequences
Splice sites
3' ss Seq
CCTCCCCTCTCTCTCCACAGCTC
3' ss Score
14.45
5' ss Seq
CATGTAAGT
5' ss Score
8.31
Exon sequences
Seq C1 exon
AACCTGAGAGCCAGAAGCAACAAAGATGCCAAGGATCCAACGACCAAGAACTCTCTGGAAA
Seq A exon
CTCTGCTCTACAAGCCTGTGGACCGTGTGACGAGGAGCACGCTGGTCCTCCAT
Seq C2 exon
GACTTGCTGAAGCACACTCCTGCCAGCCACCCTGACCACCCCTTGCTGCAGGACGCCCTCCGCATCTCACAGAACTTCCTGTCCAGCATCAATGAGGAGATCACACCCCGACGGCAGTCCATGACGGTGAAGAAGGGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186716-'20-22,'20-21,21-22=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.571 A=0.000 C2=0.268
Domain overlap (PFAM):
C1:
PF0062115=RhoGEF=PD(8.7=38.1),PF0062115=RhoGEF=PU(28.6=95.2)
A:
PF0062115=RhoGEF=FE(24.3=100)
C2:
PF0062115=RhoGEF=PD(16.4=66.0),PF0016924=PH=PU(0.6=2.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGCCAAGGATCCAACGACC
R:
TCGGGGTGTGATCTCCTCATT
Band lengths:
148-201
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)