HsaEX6032483 @ hg19
Exon Skipping
Gene
ENSG00000134215 | VAV3
Description
vav 3 guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:12659]
Coordinates
chr1:108247582-108292216:-
Coord C1 exon
chr1:108292084-108292216
Coord A exon
chr1:108291590-108291699
Coord C2 exon
chr1:108247582-108247683
Length
110 bp
Sequences
Splice sites
3' ss Seq
AGGAATATTAATTTTAACAGTGG
3' ss Score
1.78
5' ss Seq
TTTGTGAGT
5' ss Score
5.91
Exon sequences
Seq C1 exon
GCATATCTTCTTATTTGATTTGGCAGTGATCGTATGTAAGAGAAAAGGTGATAACTATGAAATGAAGGAAATAATAGATCTTCAGCAGTACAAGATAGCCAATAATCCTACAACCGATAAAGAAAACAAAAAG
Seq A exon
TGGTCTTATGGCTTCTACCTCATCCATACCCAAGGACAAAATGGGTTAGAATTTTATTGCAAAACAAAAGATTTAAAGAAGAAATGGCTAGAACAGTTTGAAATGGCTTT
Seq C2 exon
GTCTAACATAAGACCAGACTATGCAGACTCCAATTTCCACGACTTCAAGATGCATACCTTCACTCGAGTCACATCCTGCAAAGTCTGCCAGATGCTCCTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134215-'16-18,'16-16,17-18=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0016924=PH=FE(43.6=100),PF0063014=Filamin=FE(13.9=100)
A:
PF0016924=PH=FE(35.6=100),PF0063014=Filamin=PU(10.5=70.3)
C2:
PF0016924=PH=PD(1.0=2.9),PF0013017=C1_1=PU(39.6=60.0),PF144461=Prok-RING_1=PU(25.9=40.0),PF0063014=Filamin=FE(10.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCATATCTTCTTATTTGATTTGGCAG
R:
AGACTTTGCAGGATGTGACTCG
Band lengths:
219-329
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)