HsaEX6037021 @ hg38
Exon Skipping
Gene
ENSG00000185842 | DNAH14
Description
dynein axonemal heavy chain 14 [Source:HGNC Symbol;Acc:HGNC:2945]
Coordinates
chr1:225151883-225168028:+
Coord C1 exon
chr1:225151883-225152073
Coord A exon
chr1:225152697-225152883
Coord C2 exon
chr1:225167939-225168028
Length
187 bp
Sequences
Splice sites
3' ss Seq
GTTTTTCTTTTCCTCTTCAGATA
3' ss Score
11.7
5' ss Seq
CAGGTAAAT
5' ss Score
8.76
Exon sequences
Seq C1 exon
TGTGCTCTGTTTGCATTTAAATGTAACACAGCCTTAATAAAGCTTCCAAACTCACTTATAGTTTTAACATGCTTTGGACTAGAGAAAACAGTGCTAGTGATGAATACTGTAATGTCTTTTAGGTTTGTACTGGAAGGAAAAGAAATTCGTATCAATATGTCTTGTGCGGTATTTATCACCATGAATCCCAG
Seq A exon
ATACGGAGGTGGAGTAGAGCTCCCAGATAACTTAAAATCTCTGTTTCGCCCAGTGGCAATGATGGTGCCCCATTATCAAATGATTGCTGAAATAATATTGTTTTCATTTGGTTTCAAATCTGCAAATTCACTCTCTGGAAAGCTAACTAACCTTTATGAATTAGCGCGCAAACAGCTCTCACAACAG
Seq C2 exon
AAAGTAATATATACTGCAACTCAGCAATTGGGTTTACAAAACTGGTCATCTCAGAAAGAGAAGATTATACAGTTTTATAATCAACTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185842_MULTIEX2-31/72=30-34
Average complexity
C2
Mappability confidence:
96%=97=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF127742=AAA_6=PD(19.1=20.3),PF127742=AAA_6=PU(29.6=57.8)
A:
PF127742=AAA_6=FE(27.0=100)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGCTCTGTTTGCATTTAAATGT
R:
TGAGATGACCAGTTTTGTAAACCCA
Band lengths:
244-431
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains