HsaEX6038465 @ hg19
Exon Skipping
Gene
ENSG00000170558 | CDH2
Description
cadherin 2, type 1, N-cadherin (neuronal) [Source:HGNC Symbol;Acc:1759]
Coordinates
chr18:25582961-25589836:-
Coord C1 exon
chr18:25589681-25589836
Coord A exon
chr18:25585813-25585957
Coord C2 exon
chr18:25582961-25583133
Length
145 bp
Sequences
Splice sites
3' ss Seq
TTTTCTAATTACTTTTGCAGTTG
3' ss Score
8.41
5' ss Seq
CTGGTAAGT
5' ss Score
10.65
Exon sequences
Seq C1 exon
ATCAGGTCTGATAGAGATAAAAACCTTTCACTGCGGTACAGTGTAACTGGGCCAGGAGCTGACCAGCCTCCAACTGGTATCTTCATTATCAACCCCATCTCGGGTCAGCTGTCGGTGACAAAGCCCCTGGATCGCGAGCAGATAGCCCGGTTTCAT
Seq A exon
TTGAGGGCACATGCAGTAGATATTAATGGAAATCAAGTGGAGAACCCCATTGACATTGTCATCAATGTTATTGACATGAATGACAACAGACCTGAGTTCTTACACCAGGTTTGGAATGGGACAGTTCCTGAGGGATCAAAGCCTG
Seq C2 exon
GAACATATGTGATGACCGTAACAGCAATTGATGCTGACGATCCCAATGCCCTCAATGGGATGTTGAGGTACAGAATCGTGTCTCAGGCTCCAAGCACCCCTTCACCCAACATGTTTACAATCAACAATGAGACTGGTGACATCATCACAGTGGCAGCTGGACTTGATCGAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000170558-'10-9,'10-8,12-9=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.155 A=0.159 C2=0.224
Domain overlap (PFAM):
C1:
PF0002812=Cadherin=FE(53.7=100)
A:
PF0002812=Cadherin=PD(24.2=46.9),PF0002812=Cadherin=PU(10.8=22.4)
C2:
PF0002812=Cadherin=FE(55.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCCTCCAACTGGTATCTTCA
R:
CAGCTGCCACTGTGATGATGT
Band lengths:
252-397
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)