HsaEX6038508 @ hg19
Exon Skipping
Gene
ENSG00000134765 | DSC1
Description
desmocollin 1 [Source:HGNC Symbol;Acc:3035]
Coordinates
chr18:28714535-28720264:-
Coord C1 exon
chr18:28720005-28720264
Coord A exon
chr18:28719711-28719853
Coord C2 exon
chr18:28714535-28714747
Length
143 bp
Sequences
Splice sites
3' ss Seq
ATTTGATTTCTAAAAATTAGGTA
3' ss Score
4.9
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
CCATTGAACTATGAAGTCAATCGCCAAGTTATTTTGCAAGTTGGTGTCATTAACGAGGCACAATTCTCTAAAGCAGCGAGCTCACAAACTCCTACAATGTGCACTACAACTGTCACCGTTAAAATTATAGACAGTGATGAGGGCCCTGAATGCCACCCTCCAGTGAAAGTTATTCAGAGTCAAGATGGCTTCCCAGCTGGCCAAGAACTCCTTGGATACAAAGCACTGGACCCGGAAATATCCAGTGGTGAAGGCTTAAG
Seq A exon
GTATCAGAAGTTAGGGGATGAAGATAACTGGTTTGAAATTAATCAACACACTGGCGACTTGAGAACTCTAAAAGTACTAGATAGAGAATCCAAATTTGTAAAAAACAACCAATACAATATTTCAGTTGTTGCAGTGGATGCAG
Seq C2 exon
TTGGCCGATCTTGCACTGGAACATTAGTAGTTCATTTGGATGATTACAACGATCACGCACCTCAAATTGACAAAGAAGTGACCATTTGTCAGAATAATGAGGATTTTGCTGTTCTGAAACCTGTAGATCCAGATGGACCTGAAAATGGACCACCTTTTCAATTCTTTCTGGATAATTCTGCCAGTAAAAACTGGAACATAGAAGAAAAGGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134765-'9-10,'9-9,10-10=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.218 A=0.020 C2=0.139
Domain overlap (PFAM):
C1:
PF0002812=Cadherin=PD(40.0=48.3),PF0002812=Cadherin=PU(33.3=35.6)
A:
PF0002812=Cadherin=FE(51.6=100)
C2:
PF0002812=Cadherin=PD(14.0=18.1),PF0002812=Cadherin=PU(54.0=65.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCGAGCTCACAAACTCCTACA
R:
TTTGAGGTGCGTGATCGTTGT
Band lengths:
251-394
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)